Current Vacancies & Studentships
Research on multidrug resistance
Multidrug transporters mediate the active extrusion of cytotoxic agents away from their intracellular targets. They are pharmacologically important proteins in microbial pathogens that are associated with some of the most devastating diseases in the world; in this capacity they can impair antimicrobial chemotherapy.
A post-doctoral position is available for up to 2.5 years in the Department of Pharmacology, University of Cambridge, under supervision of Dr Hendrik van Veen. Van Veen’s research group aims at the molecular mechanisms of recognition and transport of chemotherapeutic drugs by efflux pumps from pathogenic bacteria and cancer cells.
The project will focus on the molecular mechanisms of tripartite drug efflux pumps, such as AcrAB-TolC and MacAB-TolC in Escherichia coli, and will involve biochemical and electrophysiological techniques in cells and artificial membrane vesicle systems to study substrate transport and its energetics. The project is funded by a programme grant of the Human Frontier Science Program Organization (HFSPO).
Applicants should be highly motivated, enthusiastic individuals, capable of thinking and working independently, and must have experience with membrane proteins. Candidates should have or shortly expect to obtain a PhD in a related subject.
Further information can be found on our website at:
Closing date: Friday 7 March 2014
Starting salary, depending on experience, will be in the range £28,132-£36,661
Candidates should submit a CV, a brief supporting statement (two sides maximum), a coversheet CHRIS 6 (available from http://www.phar.cam.ac.uk/department/vacancies) including the names and email addresses of two academic referees, to the Departmental Administrator, Ms Jessica Dunne at: firstname.lastname@example.org.
Please quote reference PL02632 on your application and in any correspondence about this vacancy.
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