skip to primary navigationskip to content



Peer-reviewed publication


  • Ducret E., Puaud M., Lacoste J., Dugast E., Belin-Rauscent A., Murray J., Everitt BJ., Houeto J. & Belin D. N-acetylcysteine facilitates self-imposed abstinence after escalation of cocaine intake. Biological Psychiatry. In Press
  • Belin-Rauscent, A., Daniel, M., Puaud, M., Jupp, B., Sawiak, S., Howett, D., Caprioli, D., Besson, M., Robbins, T.W., Everitt, B.J., Dalley, J.W. & Belin, D. From impulses to maladaptive actions: the insula is a neurobiological gate for the development of compulsive disorders. Molecular Psychiatry. In Press
  • Giuliano C, Goodlett CR, Economidou D, García-Pardo MP, Belin D, Robbins TW, Bullmore ET, Everitt BJ. A new preclinical model of alcohol seeking and drinking in alcohol-preferring rats: Selective effects of the novel µ-opioid receptor antagonist GSK1521498. Neuropsychopharmacology. In Press 
  • Belin-Rauscent A., Fouyssac M., Bonci A., Belin D. How preclinical models evolved to resemble the diagnostic criteria of drug addiction. Biological Psychiatry. In Press.
  • Brunault P, Salamé E, Jaafari N, Courtois R, Reveillère C, Silvain C, Benyamina A, Blecha L, Sainz-Barriga M, Belin D*, Balllon N*. Why do liver transplanted patients so often become obese? The addiction displacement hypothesis. Medical Hypothesis. In Press
  • Vanhille, N., Belin-Rauscent, A., Mar, A.C., Ducret, E. & Belin, D. High Locomotor Reactivity to Novelty Is Associated with an Increased Propensity to Choose Saccharin Over Cocaine: New Insights into the Vulnerability to Addiction. Neuropsychopharmacology40, 577-589.
  • Moreira, F.A., Jupp, B., Belin, D. & Dalley, J.W.  Endocannabinoids and striatal function: implications for addiction-related behaviours. Behavioural Pharmacology26, 59-72.

  • Ansquer S, Belin-Rauscent A, Dugast E, Duran T, Benatru I, Mar AC, Houeto JL, Belin D. Atomoxetine decreases the vulnerability to develop compulsivity in high impulsive rats Biological Psychiatry 15;75(10):825-32
  • Murray J, Dilleen R, Pelloux Y, Economidou D, Jordan ER, Dalley JW, Belin D* & Everitt BJ*. Trait impulsivity predicts the speed of transition to dorsolateral striatal dopamine control of cocaine seeking behavior Biological Psychiatry, 76(1):15–22.


  • Belin D, Belin-Rauscent A, Murray JE., Everitt BJ. Drug addiction: failure of control over maladaptive incentive habits Current Opinion in Neurobiology, 23(4): 564-72.
  • Besson M, Pelloux Y, Dilleen R, Theobald DT, Lyon A, Belin-Rauscent A, Robbins TW, Dalley JW, Everitt BJ*; Belin D*. Cocaine modulation of fronto-striatal expression of zif268, D2and 5-HT2c receptors in high and low impulsive rats Neuropsychopharmacology, 38(10):1963-73.


  • Murray J, Everitt BJ, Belin D. N-Acetylcysteine reduces early and late-stage cocaine seeking without affecting cocaine taking in rats. Addiction Biology. 17:437–440
  • Belin-Rauscent A, Everitt BJ, Belin D. Intrastriatal shifts mediate the development of drug seeking habits. Biological Psychiatry, 72, 343-345
  • Dilleen R, Pelloux Y, Mar AC, Molander A, Robbins TW, Everitt BJ, Dalley JW, Belin D. High anxiety is a predisposing endophenotype for loss of control over cocaine, but not heroin, self-administration   in rats. Psychopharmacology, 222, 89-89
  • Murray J, Belin D*, Everitt BJ*. Double dissociation of the dorsomedial and dorsolateral striatum control over the acquisition and performance of cocaine seeking. Neuropsychopharmacology, 37, 2456-2466
  • Jaafari N, Rachid F, Rotge JY,Polosan M, El-Hage W, Belin D, Vibert N, Pelissolo A. Safety and Efficacy of Repetitive Transcranial Magnetic Stimulation in the Treatment of Obsessive-Compulsive Disorder: A Review. World Biological Psychiatry 13:164–177


  • Molander A, Mar A, Norbury A, Steventon M, Moreno-Montoya M, Caprioli D, Theobald DEH, Belin D, Everitt BJ, Robbins TW, Dalley JW. High impulsivity predicting vulnerability to cocaine addiction in rats: Some relationship with novelty preference but not novelty reactivity, anxiety or stress. Psychopharmacology, 215:721–731
  • Belin D, Berson N, Balado E, Piazza PV, Deroche-Gamonet V High novelty preference rats are predisposed to compulsive cocaine self- administration. Neuropsychopharmacolgy, 36:569-579 F1000 Biology Factor: 6
  • Badiani A, Belin D, Eipstein D, Calu D & Shaham Y. Heroin and cocaine addictions: the differences do matter. Nature Reviews Neuroscience 12:685–700.
  • Belin D, Economidou D, Pelloux Y, Everitt BJ. Habit Formation and Compulsion. Neuromethods (53): 337-378
  • Belin D*, Daniel ML*, Lacoste J,Belin-Rauscent A., Bacconnier M., Jaafari N. Insight: perspectives étiologiques et phénoménologiques dans la psychopathologie des désordres obsessionnels compulsifs. Annales médicopsychologiques.
  • Jaafari N, Daniel ML, Lacoste J, Bacconnier M, Belin D, Rotge JY. Insight, obsession et vérification dans le trouble obsessionnel-compulsif. Annales médico-psychologiques.
  • Decressac M, Wright B, Belin D, Tyers P, Jaber M, Barker RA, Gaillard A. State-dependent effect of Neuropeptide Y on hippocampal neurogenesis: a study on wild type and R6/2 mice. Hippocampus 21, 233-238


  • McNamara R, Everitt BJ, Robbins, TW, Dalley JW and Belin D. Trait-like Impulsivity Does Not Predict Escalation of Heroin Self-Administration in the Rat. Psychopharmacology, 212:453-464
  • Théberge F, Milton A, Belin D, Lee, J & Everitt, BJ Limbic-striatal mechanisms of drug memory reconsolidation: differential circuitry for conditioned place preference and instrumental responding for conditioned reinforcement. Learning and memory 17:444-453. 
  • Besson M, Belin D, McNamara R, Theobald D, Castel A, Beckett VL, Crittenden BE, Newman A, Everitt BJ, Robbins TW and Dalley JW. Dissociable control of impulsivity by dopamine D2/3 receptors in the core and shell sub-regions of the rat nucleus accumbens. Neuropsychopharmacology, 35(2):560-569.


  • Belin D, Jonkman S, Dickinson A, Robbins TW and Everitt BJ. Parallel and integrative processes within the striatum: relevance for the neurobiology of addiction, Behavioural Brain Research, 199(1):89-102
  • Belin D, Balado E., Piazza PV. and Deroche-Gamonet V. Pattern of intake and drug craving predict the development of cocaine addiction-like behaviour in rats. Biological Psychiatry 65(10):863-868    


  • Belin D, Mar AC, Dalley JW, Robbins TW and Everitt BJ. High impulsivity predicts the switch to compulsive cocaine taking. Science, 320(5881): 1352-1355
  • Belin D and Everitt BJ. Cocaine-Seeking Habits Depend upon Dopamine-Dependent Serial Connectivity Linking the Ventral with the Dorsal Striatum. Neuron, 57:432-441
  • Everitt BJ, Belin D, Economidou D, Pelloux Y, Dalley, JW and Robbins, TW. Neural mechanisms underlying the vulnerability to develop compulsive drug seeking habits and addiction. Phil. Trans. R. Soc. B 363(1507):3125-35


Belin D, Deroche-Gamonet V, Jaber M. Cocaine-induced sensitisation is associated with altered dynamics of transcriptional responses of the dopamine transporter, tyrosine hydroxylase, and dopamine D2 receptors in C57Bl/6J mice. Psychopharmacology 193, 567-578


Belin D & Rauscent A: DeltaFosB: a molecular gate to motivational processes within the nucleus accumbens. J. Neurosci. 26(46): 11809-10


Deroche-Gamonet V., Belin D, Piazza PV. Evidence for addiction-like behaviour in the rat, Science 305(5686): 1014-7


Bezard E, Dovero S, Belin D, Duconger S, Jackson-Lewis V, Przedborski S, Piazza PV, Gross CE, Jaber M. Enriched environment confers resistance to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and cocaine: involvement of dopamine transporter and trophic factors. J.Neurosci. 23(35):10999-1007


Book chapters, books


  • Editor of the Intech Book Drug Addiction: from pathophysiology to treatment ISBN 979-953-307-092-5
  • Belin-Rauscent A., Belin D. Animal models of drug addiction In: Drug Addiction (Belin D, ed), InTech.
  • Belin-Rauscent A., Belin D. Drug addictions, general introduction In: Drug Addiction (Belin D, ed), InTech.
  • Murray JE., Lacoste J., Belin D. N-Acetylcysteine as a treatment for addiction. In: Drug Addiction (Belin, D, ed), InTech.
  • Belin-Rauscent A, Belin D. Neurobiologie des mauvaises habitudes. Biofutur 2012; 338, 39-42.
  • Belin D., Deroche-Gamonent V Responses to novelty and vulnerability to cocaine addiction. In: Addiction (Pierce, C, Kenny, P, eds), Cold Spring Harbor Laboratory Press.
  • Belin D. and Dalley J.W.: Animal models of addiction dans “Drug abuse and addiction in medical illness: causes,consequences and treatment ". Springer/Humana Press, USA. Editors Joris Verster, Kathleen Brady, Marc Galanter and Patricia Conrod


Belin D, Economidou D, Pelloux Y, Everitt BJ: Habit Formation and Compulsion in Animal Models of Drug Addiction (Olmstead C Ed.), Humana Press (citations: 7)


  • Deroche-Gamonet V., Belin D. and Piazza P.V.: Modélisation animale et bases biologiques de laddiction in comportements addictifs chez l'enfant et l'adolescence, (Krebs, MO ed.).
  • Everitt, BJ, Belin, D, Dalley, J, Robbins, TW (2010) Dopaminergic mechanisms in drug-seeking habits and the vulnerability to drug addiction. In: Dopamine Handbook (Leslie Iversen, SI, Stephen Dunnett, and Anders. Bjorklund, ed), new York: Oxford University Press. (citations: 1)
  • Belin D. and Everitt B.J., Drug addiction: the neural and psychological basis of an incentive habit, in Handbook of the Basal Ganglia, Elsevier.


Belin D., Bari A., Besson M. and Dalley J.W.: Multi-disciplinary investigations of impulsivity in animal models of attention-deficit hyperactivity disorder and drug addiction vulnerability in Endophenotypes of psychiatric and neurodegenerative disorders in animal models, Research Signpost eds, editor   Sylvie Granon.

(*: co-last author)