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Publications

References: Blood-brain barrier and red blood cells

2006

  • Wang, S., Hladky, S. B. and Barrand, M. A. (2006). Ion transporters in cultured rat brain endothelial cells. In Signal Transduction in the Blood-Brain Barriers, Ninth International Symposium, ed. Bauer H. C., Blasig I. E., Haseloff R. F. and Lametschwandtner A. Salzburg, Austria.

2005

  • Wu, C. P., Calcagno, A. M., Hladky, S. B., Ambudkar, S. V. and Barrand, M. A. (2005). Modulatory effects of plant phenols on human multidrug-resistance proteins 1, 4 and 5 (ABCC1, 4 and 5). FEBS Journal 272, 4725-4740.
  • Wu, C. P., Klokouzas, A., Hladky, S. B., Ambudkar, S. V. and Barrand, M. A. (2005). Interactions of mefloquine with ABC proteins, MRP1 (ABCC1) and MRP4 (ABCC4) that are present in human red cell membranes. Biochemical Pharmacology 70, 500-510.
  • Wu, C. P., Woodcock, H., Hladky, S. B. and Barrand, M. A. (2005). cGMP (guanosine 3',5'-cyclic monophosphate) transport across human erythrocyte membranes. Biochemical Pharmacology 69, 1257-1262.

2003

  • Barrand,M. A., Hickman, M. E., Jackman, C. E., Littlewood, C., Mitchell, J.,Taylor, C. J., Wrann, C. & Hladky, S. B. (2003). Volume-activated fluxes of [3H]-taurine, 96Rb+ and 125I- in rat brain endothelial cells. Journal of Physiology 547, PC59.
  • Klokouzas, A., Shahi, S., Hladky, S. B., Barrand, M. A. and van Veen, H. W. (2003). ABC transporters and drug resistance in parasitic protozoa. International Journal of Antimicrobial Agents 22, 301-317.

2002

  • Taylor, C. J., Bennett, G., Hladky, S. B. & Barrand, M. A. (2002). Endothelial cell ion transporters at the blood-brain barrier. Pflugers Archiv - European Journal of Physiology 443, s297.

2001

  • Klokouzas, A., Barrand, M. A. & Hladky, S. B. (2001). Effects of clotrimazole on transport mediated by multidrug resistance associated protein 1 (MRP1) in human erythrocytes and tumour cells. European Journal of Biochemistry 268, 6569-6577.

2000

  • Wheeler, R., Neo, S.-Y., Chew, J., Hladky, S.B. and Barrand, M.A. (2000) Use of membrane vesicles to investigate drug interactions with transporter proteins, P-glycoprotein and multidrug resistance-associated protein. International Journal of Clinical Pharmacology and Therapeutics (in press).
  • Hladky, S. B., K. Patel and M. A. Barrand (2000). Intracellular pH in a MRP1 overexpressing lung tumour cell line. British Journal of Pharmacology 129: 267P.

1999

  • Von Weikersthal, S.F., Barrand, M.A. and Hladky, S.B. (1999) Functional and molecular characterisation of a volume-sensitive chloride current in rat brain endothelial cells. Journal of Physiology 516, 75-84

1997

  • Hladky, S.B., Gewert, C. & Barrand, M.A. (1997) Measurement of intracellular pH using BCECF in cells containing organic anion transporters. British Journal of Pharmacology 123, 338P.
  • Von Weikersthal, S.F., Hickman, M.E., Hladky, S.B. and Barrand, M.A. (1997) Hypotonicity-induced changes in anion permeability of cultured rat brain endothelial cells. Biochimica et Biophysica Acta 1325, 99-107

Ion transport mechanisms and Bayesian single channel analysis

2002

  • Rosales, R. A., Fitzgerald, W. J. & Hladky, S. B. (2002). Kernel estimates for one- and two-dimensional ion channel dwell-time densities. Biophysical Journal 82(1), 29-35.

2001

  • Rosales, R., Stark, J. A., Fitzgerald, W. J. & Hladky, S. B. (2001). Bayesian restoration of ion channel records using hidden Markov models. Biophysical Journal 80, 1088-1103.

2000

  • Stark, J.A. and Hladky, S.B. (2000) Adjustments for the display of quantized ion channel dwell times in histograms with logarithmic bins. Biophysical Journal 78, 662-667. The Matlab code and explanatory notes are available.

1998

  • Stark, J.A., Fitzgerald, W.J. and Hladky, S.B. (1998) Idealisation of patch clamp records using an any-level local modelling scheme.Biophysical Journal 74 (2), W-Pos381. (The full poster is available as either postscript files or a pdf file)
  • Tripathi, S. & Hladky, S.B. (1998) Streaming potentials in gramicidin channels measured with ion selective microelectrodes. Biophysical Journal 74, 2912-2917.

1997

  • Stark, J.A., Fitzgerald, W.J. and Hladky, S.B. (1997) Bayesian modelling of patch-clamp records. Biophysical Journal 72, A327. (The full poster is available as either postscript files or a pdf file)

1995

  • Wang, K.-W., Tripathi, S. & Hladky, S.B. (1995) Ion binding constants for gramicidin A obtained from water permeability measurements. Journal of Membrane Biology 143, 247-257.
  • Hladky, S.B., Leung, J.C.H. & Fitzgerald, W.J. (1995) The mechanism of ion conduction by valinomycin: analysis of charge pulse responses. Biophysical Journal 69, 1758-1772.

1992

  • Hladky, S.B. (1992) Kinetic analysis of lipid soluble ions and carriers. Quarterly Reviews of Biophysics 25, 459-475

1988

  • Hladky, S.B. (1988) Gramicidin: Conclusions based on the kinetic data. Current Topics in Membranes and Transport 33,15-33