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Publications

2005

  • Murthy M, Pedemonte N, MacVinish L, Galietta L, Cuthbert A. 4-chloro-benzo[F]isoquinoline (CBIQ) is a novel activator of CFTR chloride channels at nanomolar concentrations. (2005). European J Pharmacol, 516(2):118-24
  • MacVinish L.J., Cope G., Ropenga A. & Cuthbert A.W. Chloride transporting capability of Calu-3 epithelia following persistent knockdown of the cystic fibrosis transmembrane conductance regulator, CFTR. (2007) Br J Pharmacol. Apr;150(8):1055-65
  • Edmond C.Y. U, Xin J. Zhao & L J MacVinish (2005) The effect of sildenafil on chloride secretion in normal and transgenic murine cystic fibrosis colonic epithelia. Proceedings of the British Pharmacological Society at http://www.pA2online.org/abstracts/ Vol3 Issue2 abst126P

2004

  • Szkotak, A.J., Murthy, M., MacVinish, L.J., Duszyk, M. & Cuthbert, A.W. (2004). 4-chloro-benzo[F]isoquinoline activates CFTR chloride channels and KCNN4 potassium channels in Calu-3 human airway epithelial cells. Br J Pharmacol. 2004 Jun;142(3):531-42

2003

  • Cuthbert, A.W. and MacVinish, L.J. (2003) Mechanisms of anion secretion in Calu-3 human airway epithelial cells by 7,8-benzoquinoline. Br. J. Pharmacol;140(1):81-90.
  • Cuthbert, A.W., Supuran, C.T. and MacVinish, L.J. (2003). Bicarbonate dependent chloride secretion in Calu-3 epithlia in response to 7,8-benzoquinoline. J. Physiol. 551(1): 79-92

2001

  • Duzsyk, M., MacVinish, L.J. and Cuthbert, A.W. (2001). Phenanthrolines- a new class of CFTR chloride channel openers. Brit. J. Pharmacol. 134(4):853-864

1993

  • Hyde, S.C., Gill, D.R., Higgins, C.F., Trezise, A.E.O, MacVinish, L.J., Cuthbert, A.W., Ratcliff, R., Evans, M.J. and Colledge, W.H. (1993). Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy. Nature, 362, 250-254