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ION CHANNELS: THEIR CELL BIOLOGY, STRUCTURE AND FUNCTION

murrell

Dr Ruth Murrell-Lagnado


E-Mail: rdm1003@cam.ac.uk
Tel: +44 1223 334011/334021
Fax: +44 1223 334100

Keywords

Cell biology, P2X purinoceptors, P2X4 receptor, P2X7 receptor, cell signalling, receptor assembly and trafficking, ion channels, electrophysiology, patch clamping, pain, cancer

Investigator bioghraphy

Having studied pharmacology as an undergraduate at UCL, I moved to Cambridge for my PhD and then to Oxford for a 2-year post-doctoral position. My primary research interest was the analysis of ligand and voltage gated ion channel properties using patch clamp methods. I obtained a HFSP post-doctoral fellowship to work with Rick Aldrich at Stanford University on the molecular mechanisms of Shaker potassium channel gating. I subsequently moved back to Cambridge to a lectureship in the Pharmacology Department and continued to investigate structure-function relationships within the potassium channel family. During the passed decade my research has focused on the cell biology, structure and regulation of P2X purinergic receptors within the nervous and immune systems.

Lab members