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Research Assistant/Research Associate – Bioinformatics Single Cell Genomics (Dr. Walid Khaled)

Applications are invited for a position in the Epithelial Tumour Biology group at the University of Cambridge which focuses on studying and identifying the earliest cellular changes leading to breast and lung cancer (Khaled W.T. 2015 Nat Commun, Bach K. et al. Nat Commun 2017 & Lazarus K. et al. Nat Commun 2018). In this project we will be working in collaboration with Dr. John Marioni (EBI, CRUK, CI) to build a comprehensive breast cell atlas. We will be using scRNAseq, scATACseq and CRISPR-scaring to chart the cellular changes in the breast under different healthy conditions. These tools will allow us to understand the impact of age and parity, known breast cancer risk factors, on cell fate and tissue homeostasis.

Applicants should have a strong interest in developmental biology, cancer biology and are expected to hold or obtain shortly, a PhD in the life sciences. They must have demonstrable experience in one or more of the following areas:

-       Analysing NGS data (using Unix, R, Python)

-       Studying genetically engineered mouse models (ideally breast or lung cancer models)

-       Tumour immunology

-       Cell biology

The successful applicant will be a careful and methodical worker, accurate and ready to take responsibility as part of a team.  They will be self-motivated and able to organise, perform and analyse experiments with minimal instruction. Ideally, they will have relevant laboratory experience and be able to work efficiently and productively without direct supervision. Careful observation and accurate computer-based record-keeping and presentation are essential.

To apply online for this vacancy, please click Here . This will direct you to the University's Web Recruitment System, where you will need to register an account and log in before completing the online application form. For the online application, you will need to provide your personal details, names and e-mail addresses of two referees familiar with your recent research, CV, publications and a cover letter (including a description of your experience as it relates to the job specifications). For enquiries about the online application process please contact Ms. Saez (pharsect@hermes.cam.ac.uk). Please quote reference PL18346 on your application and in any correspondence about this vacancy Applications from agencies will not be considered.

The closing date is 26th April 2019. Interviews will be carried out as applications are received.

Informal enquiries should be made to Dr. Walid T. Khaled (wtk22@cam.ac.uk).

The position is available for 3 years (subject to a probation period) in the first instance and is available from 1st May 2019 or soon thereafter.

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