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Department of Pharmacology

 

Department of Pharmacology Recent Publications: August – October 2025

Our Department has been busy publishing high-quality research across various journals. We have compiled all the publications released from August 2025 to October 2025 for your reading pleasure.

IL-17 Stimulates Sensory Neurons and Sensitises Colonic Afferents to Noxious Stimuli in a PI3K Dependent Manner in Male Mice – Bulmer Group

Fluorescent GLP1R/GIPR dual agonist probes reveal cell targets in the pancreas and brain – Cell Signalling Group

Receptor activity-modifying protein 3 enhances GLP-1-mediated insulin secretion – Cell Signalling Group

Cap-independent co-expression of dsRNA-sensing and NF-κB pathway inhibitors enables controllable self-amplifying RNA expression with reduced immunotoxicity – Smith Group

Development of D-box peptides to inhibit the anaphase-promoting complex/cyclosome – Itzhaki Group

Using modified mRNA for cardiomyocyte proliferation and cardiac genetic disease modelling and treatment Wilson Group

Defining breast epithelial cell types in the single-cell era – Khaled Group

Microscopy-based techniques for studying the material properties of biomolecular condensates in the cellular environment - Kumita Group

Split NeissLock with Spy-Acceleration Arms Mammalian Proteins for Anhydride-Mediated Cell Ligation Howarth Group

The potential for biased signalling in the P2Y receptor family of GPCRs  - Cell Signalling Group

Arabidopsis thaliana Cyclic Nucleotide-Gated Channel 19 is involved in root extracellular ATP and Pep1 signalling – Rahman Group

Obesity due to MC4R deficiency is associated with reduced cholesterol, triglycerides and cardiovascular disease risk Marti-Solano Group

Protease-activated receptor 1-mediated matrix metalloprotease signalling in sensory neurons Bulmer Group