skip to primary navigationskip to content



A large number of my publications can be downloaded from ResearchGate


  • Xu Q, Bauer R, Hendry BM, Fan TP, Zhao Z, Duez P, Simmonds MS, Witt CM, Lu A, Robinson N, Guo DA, Hylands PJ. (2013) The quest for modernisation of traditional Chinese medicine. BMC Complement Altern Med. 13(1):132. [Epub ahead of print] PMID: 23763836
  • Mohd Fauzi F, Koutsoukas A, Lowe R, Joshi K, Fan TP, Glen RC, Bender A. (2013) Chemogenomics approaches to rationalizing the Mode-of-Action of Traditional Chinese and Ayurvedic Medicines. J Chem Inf Model. 53, 661−673. [Epub ahead of print] DOI: – Top 10 paper in ACS Journal of Chemical Information and Modelling between January and March 2013.


  • Yeh JC, Garrard IJ, Cho C-WC, Bligh SWA, Lu GH, Fan TP, Fisher D (2012) Bioactivity-guided fractionation of the volatile oil of Radix Angelica sinensis designed to preserve the synergistic effects of the mixture followed by identification of the active principles. J Chromatogr A, 1236:132-138.
  • Uzner H, Bauer R, Fan TP, Guo DA, Dias A, El-Nezami H, Efferth T, Williamson EM, Heinrich M, Robinson N, Hylands PJ, Hendry BM, Cheng YC, Xu Q (2012) Traditional Chinese Medicine Research in the Post-genomic Era: Good Practice, Priorities, Challenges and Opportunities. J Ethnopharmacol 140(3): 458-468.
  • Fan TP, Deal G, Koo HL, Rees D, Sun H, Chen ST, Dou JH, Makarov VG, Pozharitskaya ON, Shikov AN, Kim YS, Huang YT, Chang YS, Jia W, Dias A, Wong VC, Chan C. (2012) Future development of global regulations of Chinese herbal products. J Ethnopharmacol 140(3): 568-586.
  • Pelkonen O, Pasanen M, Lindon JC, Chan K, Zhao LP, Deal G, Xu Q, Fan TP (2012) Omics and its potential impact on R&D and regulation of complex herbal products. Ethnopharmacol 140(3): 587-593.
  • Lv J, Chen Y, Wang QL, Tao YY, Zhao ZM, Yang L, Fan TP, Liu CH (2012) The Chinese herbal decoction Danggui Buxue Tang inhibits angiogenesis in a rat model of liver fibrosis. Evid Based Complement Alternat Med.2012;2012: 284963. Epub 2012 Jul 29.
  • Wei XH, Liu YY, Li Q, Yan L, Hu BH, Pan CS, Li ZX, Chang X, Fan JY, Zhao N, Sun K, Huang P, Wang CS, Fan TP, Han JY. (2012) Treatment of Cardiotonic Pills® after ischemia-reperfusion ameliorates myocardial fibrosis in rats.Microcirculation. 2012 Aug 22. doi: 10.1111/micc.12002. [Epub ahead of print]


  • Yeh JC, Cindrova-Davies T, Belleri M, Morbidelli L, Miller N, Cho CW, Chan K, Wang YT, Luo GA, Ziche M, Presta M, Charnock-Jones DS, Fan TP. (2011) The natural compound n-butylidenephthalide derived from the volatile oil of Radix Angelica sinensis inhibits angiogenesis in vitro and in vivo.Angiogenesis 14(2):187-197.
  • Xu SP, Yang YY, Dan Xue, Liu JX, Liu XM, Fan TP, Pan, RL, Li PT (2011) Cognitive enhancing effects of polygalasaponins hydrolysate in A25-35-induced amnesic mice. Evid Based Complement Alternat Med.2011:839720. Epub 2011 Mar 6.


  • Uzuner H, Fan TP, Dias A, Guo DA, El-Nezami HS, Xu Q. (2010) Establishing an EU-China consortium on traditional Chinese medicine research. Chin Med. 5: 42.


  • Li P, Xu G, Li SP, Wang YT, Fan TP, Zhao QS, Zhang QW. (2008) Optimizing ultraperformance liquid chromatographic analysis of 10 diterpenoid compounds in Salvia miltiorrhiza using central composite design. J Agric Food Chem. 56(4):1164-1171.
  • Cheng CW, Yeh JC, Fan TP, Smith SK, Charnock-Jones DS. (2008) Wnt5a-mediated non-canonical Wnt signalling regulates human endothelial cell proliferation and migration. Biochem Biophys Res Commun. 365(2):285-90.
  • Lee YM, Ting CM, Cheng YK, Fan TP, Wong RN, Lung ML, Mak NK. (2008) Mechanisms of 2-methoxyestradiol-induced apoptosis and G2/M cell-cycle arrest of nasopharyngeal carcinoma cells. Cancer Lett. 268(2):295-307.


  • Leung KW, Yung KL, Mak NK, Chan YS, Fan TP, Wong RN. (2007) Neuroprotective effects of ginsenoside-Rg1 in dopaminergic neurons against rotenone toxicity. Neuropharmacology, 52(3), 827-835.
  • Leung KW, Cheung LWT, Pon YL, Wong RNS, Mak NK, Fan TP, Au CL, Tombran-Tink J,Wong AST. (2007) Ginsenoside-Rb1 inhibits tube-like structure formation of endothelial cells by regulating pigment epithelium-derived factor through estrogen receptor beta. Br J Pharmacol. 152(2):207-15.
  • Leung KW, Yung KK, Mak NK, Yue PY, Luo HB, Cheng YK, Fan TP, Yeung HW, Ng TB, Wong RN. (2007) Angiomodulatory and neurological effects of ginsenosides. Curr Med Chem. 14(12):1371-80.
  • Yue PY, Mak NK, Cheng YK, Leung KW, Ng TB, Fan DT, Yeung HW, Wong RN. (2007) Pharmacogenomics and the Yin/Yang actions of ginseng: anti-tumor, angiomodulating and steroid-like activities of ginsenosides. Chin Med. 2: 6.
  • Bapna A, Federici L, Venter H, Velamakanni S, Luisi B, Fan TP, van Veen HW. (2007) Two proton translocation pathways in a secondary active multidrug transporter. J Mol Microbiol Biotechnol. 12(3-4):197-209.


  • Jin J, Shahi S, Kang HK, van Veen H, Fan TP. (2006) Metabolites of ginsenosides as novel BCRP inhibitors. Biochem Biophys Res Commun,345(4):1308-14.
  • Fan TP, Yeh JC, Leung KW, Yue PY, Wong RN. (2006) Angiogenesis: from plants to blood vessels. Trends Pharmacol Sci,27(6):297-309
  • Leung KW, Cheng YK, Mak NK, Chan KKC, Fan TP, Wong RN. (2006) Signaling pathway of ginsenoside-Rg1 leading to nitric oxide production in endothelial cells. FEBS Letters580(13):3211-16.
  • Yue PY, Wong DY, Wu PK, Leung PY, Mak NK, Yeung HW, Liu L, Cai ZW, Jiang ZH, Fan TP, Wong RN. (2006) The angiosuppressive effects of ginsenoside-Rg3. Biochem Pharm, 72(4):437-45.


  • Yue PY, Wong DY, Ha WY, Fung MC, Mak NK, Yeung HW, Leung HW, Chan K, Liu L, Fan TP, Wong RN. (2005) Elucidation of the mechanisms underlying the angiogenic effects of ginsenoside Rg(1) in vivo and in vitro. Angiogenesis. 8(3):205-16. Erratum in: Angiogenesis. 10(1):69.
  • Kok TW, Yue PY, Mak NK, Fan TP, Liu L, Wong RN. (2005) The anti-angiogenic effect of sinomenine. Angiogenesis. 8(1):3-12.


  • Bevan D, Gherardi E, Fan TP, Edwards D, Warn R. (2004) Diverse and potent activities of HGF/SF in skin wound repair.J Pathol.203(3):831-8.
  • Sengupta S, Toh S-A, Sellers LA, Skepper JN, Koolwijk P, Leung HW, Yeung HW, Wong NSR, Sasisekharan R, Fan TPD (2004). Modulating angiogenesis: the yin and the yang in ginseng. Circulation 110(10):1219-25
  • Bapna A, Vickerstaffe E, Warrington BH, Ladlow M, Fan TPD, Ley SV (2004). Polymer-assisted, multi-step solution phase synthesis and biological screening of histone deacetylase inhibitors. Org. Biomol. Chem. 2: 611-620.


  • Sengupta S, Sellers LA, Cindrova T, Skepper J, Gherardi E, Sasisekharan R, Fan TP (2003). Cyclooxygenase-2-selective nonsteroidal anti-inflammatory drugs inhibit hepatocyte growth factor/scatter factor-induced angiogenesis. Cancer Res. 63(23): 8351-8359.
  • Sengupta S, Sellers LA, Li RC, Gherardi E, Zhao G, Watson N, Sasisekharan R, Fan TP (2003). Targeting of mitogen-activated protein kinases and phosphatidylinositol 3 kinase inhibits hepatocyte growth factor/scatter factor-induced angiogenesis. Circulation 107(23): 2955-2961.
  • Sengupta S, Sellers LA, Matheson HB, Fan TP (2003). Thymidine phosphorylase induces angiogenesis in vivo and in vitro: an evaluation of possible mechanisms. Br J Pharmacol. 139(2): 219-231..
  • Sengupta S, Gherardi E, Sellers LA, Wood JM, Sasisekharan R, Fan TP (2003). Hepatocyte growth factor/scatter factor can induce angiogenesis independently of vascular endothelial growth factor. Arterioscler Thromb Vasc Biol. 23(1): 69-75.
  • Hull ML, Charnock-Jones DS, Chan CL, Bruner-Tran KL, Osteen KG, Tom BD, Fan TP, Smith SK (2003). Antiangiogenic agents are effective inhibitors of endometriosis. J Clin Endocrinol Metab. 88(6): 2889-2899.