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Publications

 

A large number of my publications can be downloaded from ResearchGate https://www.researchgate.net/profile/Tai-Ping_Fan/publications/

2019

  • Production of rosmarinic acid with ATP and CoA double regenerating system Y Yan, P Jia, Y Bai, TP Fan, X Zheng, Y Cai Enzyme and Microbial Technology 131, 109392
  • Expression and characterisation of feruloyl esterases from Lactobacillus fermentum JN248 and release of ferulic acid from wheat bran H Deng, P Jia, J Jiang, Y Bai, TP Fan, X Zheng, Y Cai International journal of biological macromolecules 138, 272-277
  • Polygala tenuifolia-Acori tatarinowii herbal pair as an inspiration for substituted cinnamic α-asaronol esters: Design, synthesis, anticonvulsant activity, and inhibition of … Y Bai, X He, Y Bai, Y Sun, Z Zhao, X Chen, B Li, J Xie, Y Li, P Jia, X Meng, ... European Journal of Medicinal Chemistry, 111650
  • Characterisation of five alcohol dehydrogenases from Lactobacillus reuteri DSM20016 Z Hu, P Jia, Y Bai, T Fan, X Zheng, Y Cai Process Biochemistry
  • Pharmacokinetics and tissue distribution evaluation of α-asaronol and its main metabolite in rats by HPLC method Y Sun, Y Bai, M Zeng, X Chen, J Xie, B Li, X He, Y Bai, P Jia, X Meng, ... Journal of pharmaceutical and biomedical analysis 172, 349-356
  • One-pot, three-step cascade synthesis of D-danshensu using engineered Escherichia coli whole cells T Xiong, J Jiang, Y Bai, TP Fan, X Zheng, Y Cai Journal of biotechnology 300, 48-54
  • Preliminary studies: the potential anti-angiogenic activities of two Sulawesi Island (Indonesia) propolis and their chemical characterization M Iqbal, T Fan, D Watson, S Alenezi, K Saleh, M Sahlan Heliyon 5 (7), e01978
  • Redox self-sufficient biocatalyst system for conversion of 3,4-Dihydroxyphenyl-l-alanine into (R)- or (S)-3,4-Dihydroxyphenyllactic acid T Xiong, J Jiang, Y Bai, TP Fan, Y Zhao, X Zheng, Y Cai Journal of industrial microbiology & biotechnology, 1-10
  • Biosynthesis of D-danshensu from L-DOPA using engineered Escherichia coli whole cells T Xiong, J Jiang, Y Bai, T Fan, Y Zhao, X Zheng, Y Cai Applied microbiology and biotechnology, 1-9
  • Site-specific immobilization of β2-AR using O6-benzylguanine derivative-functionalized supporter for high throughput receptor-targeting lead discovery J Wang, Y Wang, J Liu, Q Li, G Yin, Y Zhang, C Xiao, TP Fan, X Zhao, ... Analytical chemistry
  • Alcohol dehydrogenases from Proteus mirabilis contribute to alcoholic flavor F Yu, Y Bai, T Fan, X Zheng, Y Cai Journal of the Science of Food and Agriculture 99 (8), 4123-4128
  • Efficient Synthesis of Hydroxytyrosol from l-3,4-Dihydroxyphenylalanine Using Engineered Escherichia coli Whole Cells C Li, P Jia, Y Bai, T Fan, X Zheng, Y Cai Journal of agricultural and food chemistry 67 (24), 6867-6873
  • Tanshinol borneol ester (DBZ), a novel synthetic small molecule angiogenesis stimulator inspired by botanical formulations for angina pectoris S Liao, L Han, X Zheng, X Wang, P Zhang, J Wu, R Liu, Y Fu, J Sun, ... British journal of pharmacology
  • Site-Specific Immobilization of β₂-AR Using O⁶-Benzylguanine Derivative-Functionalized Supporter for High-Throughput Receptor-Targeting Lead Discovery Jing Wang, Yuxin Wang, Jiajun Liu, Qian Li, Guowei Yin, Yajun Zhang, Chaoni Xiao, Taiping Fan, Xinfeng Zhao, Xiaohui Zheng
  • Traditional Chinese Medicine Herbal Drugs: From Heritage to Future Developments TP Fan, Y Zhu, C Leon, G Franz, A Bender, X Zheng The Science and Regulations of Naturally Derived Complex Drugs, 59-77

2018

  • Reducing 3,4‐dihydroxyphenylpyruvic acid to d‐3,4‐dihydroxyphenyllactic acid via a coenzyme nonspecific d‐lactate dehydrogenase from Lactobacillus reuteri YH Wang, YJ Bai, TP Fan, XH Zheng, YJ Cai Journal of applied microbiology 125 (6), 1739-1748
  • Identification of a L-Lactate dehydrogenase with 3, 4-dihydroxyphenylpyruvic reduction activity for l-Danshensu production H Lu, Y Bai, T Fan, Y Zhao, X Zheng, Y Cai Process Biochemistry 72, 119-123
  • Cinnamaldehyde accelerates wound healing by promoting angiogenesis via up-regulation of PI3K and MAPK signaling pathways X Yuan, L Han, P Fu, H Zeng, C Lv, W Chang, RS Runyon, M Ishii, L Han, ... Laboratory Investigation 98 (6), 783
  • Mimicking a New 2-Phenylethanol Production Pathway from Proteus mirabilis JN458 in Escherichia coli J Liu, J Jiang, Y Bai, T Fan, Y Zhao, X Zheng, Y Cai Journal of agricultural and food chemistry 66 (13), 3498-3504
  • Cinnamaldehyde accelerates wound healing by promoting angiogenesis via up-regulation of PI3K and MAPK signaling pathways X Yuan, L Han, P Fu, H Zeng, C Lv, W Chang, RS Runyon, M Ishii, L Han, ... Laboratory Investigation 98 (6), 783
  • Mimicking a New 2-Phenylethanol Production Pathway from Proteus mirabilis JN458 in Escherichia coli J Liu, J Jiang, Y Bai, T Fan, Y Zhao, X Zheng, Y Cai Journal of agricultural and food chemistry 66 (13), 3498-3504
  • Anticonvulsant activities of α-asaronol ((E)-3′-hydroxyasarone), an active constituent derived from α-asarone X He, Y Bai, M Zeng, Z Zhao, Q Zhang, N Xu, F Qin, X Wei, M Zhao, N Wu, ... Pharmacological Reports 70 (1), 69-74
  • Application of TCM constitution in lifetime health maintenance Q Wang, M Bai, Y Yang, X Liang, P Sun, J Han, T Fan, C Yuan Journal of Traditional Chinese Medical Sciences 5 (1), 6-15
  • One-step methodology for the direct covalent capture of GPCRs from complex matrices onto solid surfaces based on the bioorthogonal reaction between haloalkane dehalogenase and … K Zeng, Q Li, J Wang, G Yin, Y Zhang, C Xiao, T Fan, X Zhao, X Zheng Chemical Science 9 (2), 446-456

2017

  • Role of medicinal plants in neurodegenerative diseases G Ratheesh, L Tian, JR Venugopal, H Ezhilarasu, A Sadiq, TP Fan, ... Biomanufacturing Reviews 2 (1), 2
  • Characterization of a d‐Lactate Dehydrogenase from Lactobacillus fermentum JN248 with High Phenylpyruvate Reductive Activity L Chen, Y Bai, TP Fan, X Zheng, Y Cai Journal of food science 82 (10), 2269-2275
  • Characterisation of a thiamine diphosphate-dependent alpha-keto acid decarboxylase from Proteus mirabilis JN458 B Wang, Y Bai, TP Fan, X , Zheng, Y Cai Food Chemistry 232, 19-24
  • Expression, purification, and characterization of a membrane-bound D-amino acid dehydrogenase from Proteus mirabilis JN458 Y Xu, Jinjin;Bai, TP Fan, X Zheng, Y Cai Biotechnology Letters, DOI: 10.1007/s10529-017-2388-0
  • Estrogen Enhances the Expression of the Multidrug Transporter Gene ABCG2—Increasing Drug Resistance of Breast Cancer Cells through Estrogen Receptors FW Chang, HC Fan, JM Liu, TP Fan, J Jing, CL Yang, RJ Hsu International journal of molecular sciences 18 (1), 163

2016

  • BACE1 molecular docking and anti-Alzheimer's disease activities of ginsenosides RJ Choi, A Roy, HJ Jung, MY Ali, BS Min, CH Park, T Yokozawa, TP Fan, ... Journal of ethnopharmacology 190, 219-230
  • 11th German Conference on Chemoinformatics (GCC 2015) U Fechner, C de Graaf, AE Torda, S Güssregen, A Evers, H Matter, ... Journal of cheminformatics 8 (1), 18
  • Research Article Global Mapping of Traditional Chinese Medicine into Bioactivity Space and Pathways Annotation Improves Mechanistic Understanding and Discovers Relationships … SZM Zobir, FM Fauzi, S Liggi, G Drakakis, X Fu, TP Fan, A Bender
  • Global mapping of traditional chinese medicine into bioactivity space and pathways annotation improves mechanistic understanding and discovers relationships between therapeutic … M Zobir, S Zuraidah, F Mohd Fauzi, S Liggi, G Drakakis, X Fu, TP Fan, ... Evidence-Based Complementary and Alternative Medicine 2016

2015

  • A metabolite of Danshen formulae attenuates cardiac fibrosis induced by isoprenaline, via a NOX 2/ROS/p38 pathway Q Yin, H Lu, Y Bai, A Tian, Q Yang, J Wu, C Yang, TP Fan, Y Zhang, ... British journal of pharmacology 172 (23), 5573-5585
  • The polypharmacokinetics of herbal medicines W Jia, TP Fan, X Wang, G Xie Science 350 (6262 Suppl), S76-8
  • 3, 4-dihydroxyl-phenyl lactic acid restores NADH dehydrogenase 1 α subunit 10 to ameliorate cardiac reperfusion injury XY Yang, K He, CS Pan, Q Li, YY Liu, L Yan, XH Wei, BH Hu, X Chang, ... Scientific reports 5, 10739
  • Binding mechanism of nine N-phenylpiperazine derivatives and α 1A-adrenoceptor using site-directed molecular docking and high performance affinity chromatography XF Zhao, J Wang, GX Liu, TP Fan, YJ Zhang, J Yu, SX Wang, ZJ Li, ... RSC Advances 5 (70), 57050-57057
  • Bridging the seen and the unseen: a systems pharmacology view of herbal medicine Y Schroen, M Wang, HA van Wietmarschen, R Witkamp, T Hankemeier, ... Science 350 (6262), S66-S69
  • Recent novel high-tech researches in molecular biology CYC Chen, KC Chou, JD Adams, TP Fan, G Litscher BioMed research international 2015
  • Ginseng: a panacea linking East Asia and North America? R Choi, AST Wong, W Jia, IM Chang, RNS Wong, TP Fan, YS Kim Science
  • Deciphering ancient combinatorial formulas: the Shexiang Baoxin pill RH Liu, RS Runyon, YC Wang, SG Oliver, TP Fan, WD Zhang Science 347 (6219), S40-S42
  • A novel drug discovery strategy inspired by traditional medicine philosophies X Zhao, X Zheng, TP Fan, Z Li, Y Zhang, J Zheng Science 347 (6219), S38-S40
  • Herbal genomics: examining the biology of traditional medicines S Chen, J Song, C Sun, J Xu, Y Zhu, R Verpoorte, TP Fan Science 347 (6219), S27-S29

2014

  • Oriented immobilisation of histidine-tagged protein and its application in exploring interactions between ligands and proteins X Zhao, Q Li, C Xiao, Y Zhang, L Bian, J Zheng, X Zheng, Z Li, Y Zhang, ... Analytical and bioanalytical chemistry 406 (12), 2975-2985
  • The Vaso-and Neuro-protective Activities of Medicinal Herbs for Alzheimer's Disease RJ Choi, X Meng, X Zheng, TP Fan 第十四届全国中药和天然药物学术研讨会论文摘要
  • DBZ, a novel synthetic compound inspired by Compound Danshen Dripping Pills, promotes angiogenesis in vitro through activating Akt and MAPK signalling pathways S Liao, TP Fan, X Zhao, R Choi, X Zheng European Journal of Integrative Medicine 6 (6), 688
  • Integrating traditional medicine into modern health care TP Fan, J Briggs, L Liu, A Lu, J Van der Greef, A Xu Science 346 (6216), S4-S4
  • Memory-Enhancing Effects of the Crude Extract of Polygala Z Li, Y Liu, L Wang, X Liu, Q Chang, Z Guo, Y Liao, R Pan, TP Fan
  • Chemoghemogenomics approaches in rationalizing compound action of traditional Chinese and Ayurvedic medicines FM Fauzi, A Koutsoukas, R Lowe, K Joshi, TP Fan, A Bender European Journal of Integrative Medicine 1 (6), 131-132
  • Memory-enhancing effects of the crude extract of Polygala tenuifolia on aged mice Z Li, Y Liu, L Wang, X Liu, Q Chang, Z Guo, Y Liao, R Pan, TP Fan Evidence-Based Complementary and Alternative Medicine 2014
  • Why is research on herbal medicinal products important and how can we improve its quality? O Pelkonen, Q Xu, TP Fan Journal of traditional and complementary medicine 4 (1), 1-7
  • Network pharmacology in traditional chinese medicine S Li, TP Fan, W Jia, A Lu, W Zhang Evidence-based complementary and alternative medicine 2014

2013

  • Xu Q, Bauer R, Hendry BM, Fan TP, Zhao Z, Duez P, Simmonds MS, Witt CM, Lu A, Robinson N, Guo DA, Hylands PJ. (2013) The quest for modernisation of traditional Chinese medicine. BMC Complement Altern Med. 13(1):132. [Epub ahead of print] PMID: 23763836
  • Mohd Fauzi F, Koutsoukas A, Lowe R, Joshi K, Fan TP, Glen RC, Bender A. (2013) Chemogenomics approaches to rationalizing the Mode-of-Action of Traditional Chinese and Ayurvedic Medicines. J Chem Inf Model. 53, 661−673. [Epub ahead of print] DOI: – Top 10 paper in ACS Journal of Chemical Information and Modelling between January and March 2013.

2012

  • Yeh JC, Garrard IJ, Cho C-WC, Bligh SWA, Lu GH, Fan TP, Fisher D (2012) Bioactivity-guided fractionation of the volatile oil of Radix Angelica sinensis designed to preserve the synergistic effects of the mixture followed by identification of the active principles. J Chromatogr A, 1236:132-138.
  • Uzner H, Bauer R, Fan TP, Guo DA, Dias A, El-Nezami H, Efferth T, Williamson EM, Heinrich M, Robinson N, Hylands PJ, Hendry BM, Cheng YC, Xu Q (2012) Traditional Chinese Medicine Research in the Post-genomic Era: Good Practice, Priorities, Challenges and Opportunities. J Ethnopharmacol 140(3): 458-468.
  • Fan TP, Deal G, Koo HL, Rees D, Sun H, Chen ST, Dou JH, Makarov VG, Pozharitskaya ON, Shikov AN, Kim YS, Huang YT, Chang YS, Jia W, Dias A, Wong VC, Chan C. (2012) Future development of global regulations of Chinese herbal products. J Ethnopharmacol 140(3): 568-586.
  • Pelkonen O, Pasanen M, Lindon JC, Chan K, Zhao LP, Deal G, Xu Q, Fan TP (2012) Omics and its potential impact on R&D and regulation of complex herbal products. Ethnopharmacol 140(3): 587-593.
  • Lv J, Chen Y, Wang QL, Tao YY, Zhao ZM, Yang L, Fan TP, Liu CH (2012) The Chinese herbal decoction Danggui Buxue Tang inhibits angiogenesis in a rat model of liver fibrosis. Evid Based Complement Alternat Med.2012;2012: 284963. Epub 2012 Jul 29.
  • Wei XH, Liu YY, Li Q, Yan L, Hu BH, Pan CS, Li ZX, Chang X, Fan JY, Zhao N, Sun K, Huang P, Wang CS, Fan TP, Han JY. (2012) Treatment of Cardiotonic Pills® after ischemia-reperfusion ameliorates myocardial fibrosis in rats.Microcirculation. 2012 Aug 22. doi: 10.1111/micc.12002. [Epub ahead of print]

2011

  • Yeh JC, Cindrova-Davies T, Belleri M, Morbidelli L, Miller N, Cho CW, Chan K, Wang YT, Luo GA, Ziche M, Presta M, Charnock-Jones DS, Fan TP. (2011) The natural compound n-butylidenephthalide derived from the volatile oil of Radix Angelica sinensis inhibits angiogenesis in vitro and in vivo.Angiogenesis 14(2):187-197.
  • Xu SP, Yang YY, Dan Xue, Liu JX, Liu XM, Fan TP, Pan, RL, Li PT (2011) Cognitive enhancing effects of polygalasaponins hydrolysate in A25-35-induced amnesic mice. Evid Based Complement Alternat Med.2011:839720. Epub 2011 Mar 6.

2010

  • Uzuner H, Fan TP, Dias A, Guo DA, El-Nezami HS, Xu Q. (2010) Establishing an EU-China consortium on traditional Chinese medicine research. Chin Med. 5: 42.

2008

  • Li P, Xu G, Li SP, Wang YT, Fan TP, Zhao QS, Zhang QW. (2008) Optimizing ultraperformance liquid chromatographic analysis of 10 diterpenoid compounds in Salvia miltiorrhiza using central composite design. J Agric Food Chem. 56(4):1164-1171.
  • Cheng CW, Yeh JC, Fan TP, Smith SK, Charnock-Jones DS. (2008) Wnt5a-mediated non-canonical Wnt signalling regulates human endothelial cell proliferation and migration. Biochem Biophys Res Commun. 365(2):285-90.
  • Lee YM, Ting CM, Cheng YK, Fan TP, Wong RN, Lung ML, Mak NK. (2008) Mechanisms of 2-methoxyestradiol-induced apoptosis and G2/M cell-cycle arrest of nasopharyngeal carcinoma cells. Cancer Lett. 268(2):295-307.

2007

  • Leung KW, Yung KL, Mak NK, Chan YS, Fan TP, Wong RN. (2007) Neuroprotective effects of ginsenoside-Rg1 in dopaminergic neurons against rotenone toxicity. Neuropharmacology, 52(3), 827-835.
  • Leung KW, Cheung LWT, Pon YL, Wong RNS, Mak NK, Fan TP, Au CL, Tombran-Tink J,Wong AST. (2007) Ginsenoside-Rb1 inhibits tube-like structure formation of endothelial cells by regulating pigment epithelium-derived factor through estrogen receptor beta. Br J Pharmacol. 152(2):207-15.
  • Leung KW, Yung KK, Mak NK, Yue PY, Luo HB, Cheng YK, Fan TP, Yeung HW, Ng TB, Wong RN. (2007) Angiomodulatory and neurological effects of ginsenosides. Curr Med Chem. 14(12):1371-80.
  • Yue PY, Mak NK, Cheng YK, Leung KW, Ng TB, Fan DT, Yeung HW, Wong RN. (2007) Pharmacogenomics and the Yin/Yang actions of ginseng: anti-tumor, angiomodulating and steroid-like activities of ginsenosides. Chin Med. 2: 6.
  • Bapna A, Federici L, Venter H, Velamakanni S, Luisi B, Fan TP, van Veen HW. (2007) Two proton translocation pathways in a secondary active multidrug transporter. J Mol Microbiol Biotechnol. 12(3-4):197-209.

2006

  • Jin J, Shahi S, Kang HK, van Veen H, Fan TP. (2006) Metabolites of ginsenosides as novel BCRP inhibitors. Biochem Biophys Res Commun,345(4):1308-14.
  • Fan TP, Yeh JC, Leung KW, Yue PY, Wong RN. (2006) Angiogenesis: from plants to blood vessels. Trends Pharmacol Sci,27(6):297-309
  • Leung KW, Cheng YK, Mak NK, Chan KKC, Fan TP, Wong RN. (2006) Signaling pathway of ginsenoside-Rg1 leading to nitric oxide production in endothelial cells. FEBS Letters580(13):3211-16.
  • Yue PY, Wong DY, Wu PK, Leung PY, Mak NK, Yeung HW, Liu L, Cai ZW, Jiang ZH, Fan TP, Wong RN. (2006) The angiosuppressive effects of ginsenoside-Rg3. Biochem Pharm, 72(4):437-45.

2005

  • Yue PY, Wong DY, Ha WY, Fung MC, Mak NK, Yeung HW, Leung HW, Chan K, Liu L, Fan TP, Wong RN. (2005) Elucidation of the mechanisms underlying the angiogenic effects of ginsenoside Rg(1) in vivo and in vitro. Angiogenesis. 8(3):205-16. Erratum in: Angiogenesis. 10(1):69.
  • Kok TW, Yue PY, Mak NK, Fan TP, Liu L, Wong RN. (2005) The anti-angiogenic effect of sinomenine. Angiogenesis. 8(1):3-12.

2004

  • Bevan D, Gherardi E, Fan TP, Edwards D, Warn R. (2004) Diverse and potent activities of HGF/SF in skin wound repair.J Pathol.203(3):831-8.
  • Sengupta S, Toh S-A, Sellers LA, Skepper JN, Koolwijk P, Leung HW, Yeung HW, Wong NSR, Sasisekharan R, Fan TPD (2004). Modulating angiogenesis: the yin and the yang in ginseng. Circulation 110(10):1219-25
  • Bapna A, Vickerstaffe E, Warrington BH, Ladlow M, Fan TPD, Ley SV (2004). Polymer-assisted, multi-step solution phase synthesis and biological screening of histone deacetylase inhibitors. Org. Biomol. Chem. 2: 611-620.

2003

  • Sengupta S, Sellers LA, Cindrova T, Skepper J, Gherardi E, Sasisekharan R, Fan TP (2003). Cyclooxygenase-2-selective nonsteroidal anti-inflammatory drugs inhibit hepatocyte growth factor/scatter factor-induced angiogenesis. Cancer Res. 63(23): 8351-8359.
  • Sengupta S, Sellers LA, Li RC, Gherardi E, Zhao G, Watson N, Sasisekharan R, Fan TP (2003). Targeting of mitogen-activated protein kinases and phosphatidylinositol 3 kinase inhibits hepatocyte growth factor/scatter factor-induced angiogenesis. Circulation 107(23): 2955-2961.
  • Sengupta S, Sellers LA, Matheson HB, Fan TP (2003). Thymidine phosphorylase induces angiogenesis in vivo and in vitro: an evaluation of possible mechanisms. Br J Pharmacol. 139(2): 219-231..
  • Sengupta S, Gherardi E, Sellers LA, Wood JM, Sasisekharan R, Fan TP (2003). Hepatocyte growth factor/scatter factor can induce angiogenesis independently of vascular endothelial growth factor. Arterioscler Thromb Vasc Biol. 23(1): 69-75.
  • Hull ML, Charnock-Jones DS, Chan CL, Bruner-Tran KL, Osteen KG, Tom BD, Fan TP, Smith SK (2003). Antiangiogenic agents are effective inhibitors of endometriosis. J Clin Endocrinol Metab. 88(6): 2889-2899.