Submitted by D.P. Juan on Tue, 29/07/2025 - 10:00
The UK’s proteostasis capability has been bolstered by the award of a BBSRC Network Grant to support the future development of the UK Proteostasis Network from 2025-2028.
Proteostasis, an umbrella term that describes the synthesis, folding, trafficking and degradation of proteins, is essential to maintaining the correct function of our cells, tissues, organs and therefore vital to health. These conserved protein quality control (PQC) processes are coordinated across biological scale (from molecules, organelles, cells, tissues, to organismal level) and are critical to enable responses to physiological and stress-related cues. Examples of failures in these quality control mechanisms include toxic protein aggregation, such as seen in Alzheimer's disease.
Professor Laura Itzhaki and Dr Ritwick Sawakar have been deeply involved in the inception and organisation of this new Network.
A full news release can be read here: https://www.babraham.ac.uk/news/2025/07/uk-proteostasis-network-receives...