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Molecular mechanisms of multidrug transporters: from bacteria to man

 

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Dr Hendrik Van Veen - Group leader

NST IB Pharmacology Course Organiser
E-Mail: hwv20@cam.ac.uk
Tel: +44 1223 765295/334073
Fax: +44 1223 334100

Keywords

Antibiotic resistance, antimicrobial resistance (AMR), anticancer drug resistance, membrane transporters, multidrug transporters, drug efflux, molecular basis of drug recognition, mechanisms of transport, bioenergetics, inhibitors

Investigator biography:

Hendrik van Veen earned his B.Sc. and M.Sc. degrees in Biochemistry and PhD degree in Microbiology (supervisors Profs. Alex Zehnder and Wil Konings) cum laude at Wageningen University, the Netherlands. In 1996, his thesis on solute transport in bacteria was awarded the Kluyver Award of the Netherlands Society of Microbiology. After post-doctoral work at the Universities of Groningen (Prof. Wil Konings) and Oxford (Prof. Chris Higgins), he received a research fellowship from the Royal Netherlands Academy of Arts and Sciences (KNAW) to work on bacterial multidrug resistance at Groningen University. During this time, he obtained a Max Gruber Award in Biochemistry from the University of Groningen. In 2001 he became associated with the University of Cambridge, Department of Pharmacology, first as a University Lecturer (2001) and University Senior Lecturer (2004) and currently as Reader in Molecular Pharmacology (2013). He is a teaching fellow at Clare College, a regional fellow of the Royal Society of Medicine, and leader of a research group aiming at the mechanisms of antibiotic and anticancer drug recognition and transport by multidrug transporters in pro- and eukaryotic cells. He was a member of the College of Experts of the Medical Research Council from 2004 to 2009, and serves on various editorial boards, and committees of funding agencies and societies.

Lab members

Dr Kelvin Agboh  -    Dr Lisa Fagg  -  Ms Anam Ali -   -  Ms Zhen Tong