– Group Leader
Fellow in Pharmacology Jesus College
Thrombosis, Thrombocytopenia, Platelets, Cancer chemotherapy, Cellular signalling, Cell death, Calcium ,Apoptosis, Necrosis. Phosphatidylserine exposure
Harper MT, Camacho Londono JE, Quick K, Camacho Londono J, Philipp SE, Birnbaumer L, Freichel M, Poole AW (2013). Transient receptor potential channels function as a coincidence signal detector mediated phosphatidylserine exposure. Science Signalling, 6, ra50.
Harper MT, Poole AW. Chloride channels are necessary for full platelet phosphatidylserine exposure and procoagulant activity. Cell Death Dis, 4, e969.
Harper MT, Poole AW (2012). Bcl-xL –inhibitory BH3 mimetic ABT-737 depletes platelet calcium stores. Blood, 119, 4337-4338.
Harper MT, Poole AW (2011). Contribution of store-operated calcium entry and non-capacitative calcium entry to thrombin-induced calcium signalling in human platelets. Cell Calcium, 50, 351-358.
Harper MT, Poole AW (2011). PKC inhibition enhances Ca2+ signalling and phosphatidylserine exposure downstream of protease-activated receptor-1 but not protease-activated receptor-4 in human platelets. J Thromb Haemost, 9, 1599-1607.
If you are interested in our research (all levels from undergrad to postdoc), please contact Matthew.