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Dr Tai-Ping Fan

Dr Tai-Ping Fan

University Senior Lecturer

Angiogenesis and Natural Products Laboratory


Office Phone: +44 (0) 1223 3 34015 / Lab: 3 34025

Keywords

  • Vascular pharmacology; angiogenesis; immunopharmacology; traditional medicine and natural products

Topics

  • Vascular Pharmacology

Key Publications

Sengupta S, Toh S-A, Sellers LA, Skepper JN, Koolwijk P, Leung HW, Yeung HW, Wong NSR, Sasisekharan R, Fan TPD (2004). Modulating angiogenesis: the yin and the yang in ginseng. Circulation 110(10):1219-25

Fan TP, Yeh JC, Leung KW, Yue PY, Wong RN. (2006) Angiogenesis: from plants to blood vessels. Trends Pharmacol Sci,27(6):297-309

Mohd Fauzi F, Koutsoukas A, Lowe R, Joshi K, Fan TP, Glen RC, Bender A. (2013) Chemogenomics approaches to rationalizing the Mode-of-Action of Traditional Chinese and Ayurvedic Medicines. J Chem Inf Model. 53, 661−673. DOI: 10.1021/ci3005513 – The top paper in ACS Journal of Chemical Information and Modelling in 2013.

 

Investigator biography

Capitalizing on his experience in immunopharmacology, Tai-Ping Fan embarked on a quest to transform the art of ethnopharmacology into a rigorous evidence-based science of healthcare and wellness. With an interdisciplinary approach, he and his collaborators have investigated the cellular and molecular mechanisms of angiogenesis. From clinically effective herbs, they use ‘omics to discover and optimize phytochemicals for prevention/treatment of diseases where there is excessive (e.g. cancer, atherosclerosis) or inadequate angiogenesis (e.g. myocardial infarct, chronic wound). He was the Founding Editor-in-Chief of ANGIOGENESIS (1997-2004), and a Deputy Coordinator of an FP7-funded Coordination Action - Good Practice in TCM Research in the Post-genomic Era (GP-TCM; 2009-2012). The overall aim of the project was to inform best practices and harmonize research of the safety and efficacy of TCM in EU Member States and China using a functional genomics approach. Specifically, he led a work package on the global regulation of botanical drugs and herbal products. As Secretary-General of GP-TCM Research Association (http://www.gp-tcm.org), he has been commissioned by Science to edit a Special Feature on Traditional Medicine in 2014. This unique collection of perspectives will focus on recent advances in the standardization, safety, R&D and regulation of materia medica used in traditional medicine of different ethnic origins.