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Seminars & Events

Department of Pharmacology Tea Club


tea clubTea Club will be held as usual in the Departmental Lecture Theatre at 4 pm on Fridays in Full Term. After the talk there will be wine and nibbles and a chance to talk informally with the speaker. If anyone wishes to have some time with any speaker before the talk, or have dinner with them afterwards, please contact  in advance.





Lent 2017

Tea Club Seminars


20th January
Andreas Bender From virtual screening to mode of action analysis: How computers can help chemical biology and drug discovery
Centre for Molecular Informatics, University of Cambridge

27th January
Wenshu Xu  Macrocyclized extended peptides: Inhibiting the substrate-recognition domain of tankyrase
Department of Pharmacology, University of Cambridge

3rd  February
David Poyner How does CGRP activate its receptor? An odyssey of a family B G-protein coupled receptor
Aston University

10th February
Amrita Ahluwalia A reductionist approach to cardiovascular disease: Inorganic nitrate to nitrite to NO
William Harvey Research Institute, Queen Mary University of London

17th February
Norman Davey Decoding the hidden regulatory landscape of the proteome
University College Dublin

24th February
Margaret Ashcroft Exploring the molecular interface between mitochondria and the cellular oxygen-sensing machinery
University of Cambridge

3rd March
Sussan Nourshargh Neutrophil transmigration in vivo: Modes, mechanisms and pathogenesis
William Harvey Research Institute, Queen Mary University of London

10th March
Charlotte Summers  The role of neutrophil-endothelial interactions in modulating lung inflammation
Department of Anaesthesia, University of Cambridge



Previous Tea Club seminars:


Michaelmas 2016

Tea Club Seminars


7th October
Aylin Hanyaloglu Multi-Dimensional Programming of G Protein-Coupled Receptor Signalling: Mechanisms and Applications
Imperial College London

14th October
Martin Bushall How Do MicroRNAs Work?
MRC Toxicology Unit, Leicester

21st October
Thora Karadottir Neuronal Regulation of Myelination and Remyelination
Cambridge Stem Cell Institute

28th October
Ken Meissner Quantum Dots and Microspheres and Red Blood Cells, Oh My!
University of Swansea

4th November
Sandip Patel Non-canonical Signalling Through Acidic Calcium Stores
University College London

11th November
Graham Ladds Systems analysis of G protein-coupled receptor pharmacology
Department of Pharmacology, University of Cambridge

18th November
Jules Griffin From mouse to man and back again, applications of metabolomics (and lipidomics) to type 2 diabetes
Department of Biochemistry, University of Cambridge

25th November
Kyren Lazarus Understanding the Role of BCL11A in Triple Negative Breast Cancer
Department of Pharmacology, University of Cambridge


Lent 2016

Tea Club Seminars

22nd January
Meritxell Huch To be confirmed
Department of Physiology, Development & Neuroscience, University of Cambridge

29th January
Ian Prior Isoform and codon-specific Ras signalling
University of Liverpool

5th February
Alastair Poole Platelets: from biogenesis to function
University of Bristol

12th February
Victoria Chapman Pharmacological studies of peripheral versus central mechanisms of arthritis pain
University of Nottingham

19th February
Richard Gilbertson Mapping Cancer Origins
Cambridge Cancer Centre

26th February
Cath Lindon Ubiquitin-mediated pathways in proteostasis and cell division
Department of Pharmacology, University of Cambridge

4th March
Graham Ladds Signalling bias at G protein-coupled receptors
Department of Pharmacology, University of Cambridge



Michaelmas 2015

Tea Club Seminars


October 9th Mathew Garnett (Wellcome Trust Sanger Institute, University of Cambridge
‘High-throughput approaches in cancer cell models to enable precision cancer medicine’

 Oct 16th Darren Cross, Richard A Ward, Ray Finlay (AstraZeneca Oncology Innovative Medicines)
‘Inhibition of EGF receptor signalling: The Discovery of AZD9291’

Oct 23rd Margaret Cunningham (University of Strathclyde)
‘Probing thrombin-mediated platelet function using novel cyclic pepducins that target discrete regions of proteinase-activated receptor-4 (PAR4)’

Oct 30th David Beech (University of Leeds)
‘The magic of calcium ion entry: discovery, disease and drugs’

Nov 6th Mike Murphy (MRC Mitochondrial Biology Unit, University of Cambridge)
‘How mitochondrial ROS contribute to pathologies: mechanisms and potential therapies'

Nov 13th Irene Tracey (Nuffield Department of Clinical Neurosciences, University of Oxford)

Nov 20th Tim Warner (William Harvey Research Institute, London)
‘Platelets in time and space: understanding the actions of anti-platelet drugs within the body’

Nov 27th Elizabeth Murchison (Department of Veterinary Medicine, University of Cambridge)
‘Genome diversity and evolution of transmissible cancers in dogs and Tasmanian devils’

(Tea Club Organiser)


Lent 2015

Tea Club Seminars


Jan 16th Ken Smith (CIMR and Dept of Medicine.Cambridge)

‘Genomics, immunity and the biology of clinical outcome.’

Jan 23rdWendy Bickmore (MRC Human Genetics Unit, Edinburgh)

‘Spatial Genome Organisation and gene regulation.’

Jan 30th Maria Fitzgerald (Dept of Neuroscience, Physiology & Pharmacology, UCL)

'The developing pain system: a lifelong story.'

Feb 6thPhill Hawkins (Babraham Institute, Cambridge)

‘PI3Ks; the rules of engagement.’

Feb 13th Pooneh Bagher (Dept of Pharmacology, Oxford)

‘Illuminating the lumen: endothelial calcium in both vasoconstriction and vasodilation.’

Feb 20th Kim Nasmyth (Dept of Biochemistry, Oxford)

‘How are chromosomes held together?’

Feb 27th Ann Ferguson-Smith (Dept of Genetics, Cambridge)

‘Parental-origin effects and the epigenetic control of genome function.’

Mar 6th Tony Kouzarides (Gurdon Institute and Dept of Pathology, Cambridge)

‘Epigenetic pathways in transcription and cancer.’

(Tea Club Organiser)

Michaelmas 2014

Tea Club Seminars


Oct 17th Stephen O’Rahilly (Metabolic Research Laboratories, Cambridge)
‘Human obesity and insulin resistance: lessons from genetics’

Oct 24th Momo Bentires-Alj (Friedrich Miescher Institute, Basel)
‘Targeted cancer therapy: act locally, think globally’

Oct 31st Sue Jones (PDN, Cambridge)
‘Regulation of NMDA receptor activity in substantia nigra dopamine neurons’

Nov 7th Steve Royle (Medical Cell Biology, Warwick)
‘How and why cells switch off clathrin-mediated endocytosis during mitosis’

Nov 14th Tony Jackson (Biochemistry Dept, Cambridge)
‘A proteomic method for characterising local protein clusters on the plasma membrane'

Nov 21nd Wolf Reik (Babraham Institute, Cambridge)
‘Epigenetic reprogramming in mammalian development’

Nov 28th Dermot Cooper (Dept of Pharmacology, Cambridge)
‘Adenylyl cyclases – an evolving story’

(Tea Club Organiser)

Lent 2014

Tea Club Seminars


Jan 17th Julian Downward (CRUK, London Research Laboratories)
“Mechanisms of transformation by RAS oncogenes: searching for novel therapeutic

Jan 24th Alex Gourine (Neuroscience, Physiology and Pharmacology, UCL)
“Astroglial control of vital neural networks.”

Jan 31st Giles Hardingham (Centre for Intergrative Physiology Edinburgh)
“Ca2+ signaling and the control of survival and death in neurons.”

Feb 7th Klaus Okkenhaug (Babraham Institute, Cambridge)
“PI3Ks in immunity, infection and cancer.”

Feb 14th David Belin (Pharmacology, Cambridge)
“Probing the effectiveness of new drugs to treat addictions: what is it you want to
measure, and how do you achieve it?”

Feb 21st Frances Platt (Pharmacology, Oxford)
“Lysosomal storage disorders: unanticipated links to more common diseases.”

Feb 28th Jenny Pell (Pharmacology, Cambridge)
“Epigenetic regulation of muscle stem cell fate: generation of an ageing paradigm.”

March 7th Laura Itzhaki (Pharmacology, Cambridge)
“Tandem repeat proteins: function, malfunction and therapeutic intervention.”


 (Tea Club Organiser)



Michaelmas 2013

Tea Club Seminars


Oct 11th Robin May (School of Biosciences, Birmingham)

‘Host-pathogen interactions during fatal fungal infections.’


Oct 18th Rafael Carozo Salas (Gurdon Institute, Cambridge)

‘Discovering genes and reconstructing pathways using microscopy-based functional genomics’.


Oct 25th Akhilesh Reddy (Clinical Neurosciences, Cambridge)

‘Redox and metabolic oscillations in the clockwork’.


Nov 1st Steve Tovey & Jon Clarke (Pharmacology, Cambridge)

‘cAMP directs IP3-evoked Ca2+ signalling to different intracellular Ca2+ stores,’ and ‘Regulation and function of PI5P 4-kinases’.


Nov 8th David Komander (LMB, Cambridge)

‘Mechanisms, functions and uses of OTU domain deubiquitinases.’


Nov 15th Dan Davis (Centre for Inflammation Research, Manchester)

'Using super-resolution microscopy to watch immune cells kill.'


Nov 22nd Azim Surani (Gurdon Institute, Cambridge)

‘Specification and programming of the germline for mammalian development.’


Nov 29th Anant Parekh (Physiology, Anatomy and Genetics, Oxford)

‘Decoding local calcium signals: excitation-transcription coupling.’


Robin Irvine (Tea Club Organiser)