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Postdoctoral Research Associate in G protein-coupled receptor pharmacology (Fixed Term)

DEPARTMENT/LOCATION:     Department of Pharmacology, Central Cambridge

SALARY:                               £32,816-£40,322

REFERENCE:                        PL25258

CLOSING DATE:                   24 January 2021

Applications are invited for a Postdoctoral Research Associate position in the University of Cambridge,
Department of Pharmacology, central Cambridge, working in the laboratory of Dr Graham Ladds. The lab uses
multidisciplinary approaches to investigate G protein-couped receptor (GPCR) signalling and enjoys
collaborations with both academia and industry. Webpage ( and
twitter (@GPCR_Ladds). This project has arisen through a direct collaboration with Takeda Pharmaceuticals.
The successful candidates should have (or be close to completing) a PhD in one of the following:
Pharmacology, Biochemistry, Medicine or a related field. The project focusses upon GPCR pharmacology so
experience in the used of mammalian tissue culture and BRET-based assays for GPCR research would be an
advantage. The appointee will be enthusiastic, methodical, work effectively as part of a team, be able to perform
and analyse experiments with appropriate supervision, willing to engage with the research literature, and able to
write regular research reports. Experience of using GraphPad Prism is desired but not essential.

Funds are available for a fixed term of 30 months, after probationary review and is available immediately. The
salary range for Research Associate is £32,816-£40,322.

Key duties will be to design, perform and analyse how the key regulatory proteins receptor activity modifying
proteins (RAMPs) contribute to the gastric inhibitory polypeptide (GIP) receptor pharmacology. We will be
studying GIPR agonist bias and cellular trafficking. We are keen to explore new signalling pathways modulate
by GIPR and to determine how RAMPs influence these responses. Training in these techniques will be
provided. This work builds upon ongoing projects in the Ladds-GPCR lab. More details are available on

Fixed-term: The funds for this post are available for 30 months in the first instance.

To apply online for this vacancy and to view further information about the role, please visit :

For the online application you will need to provide your personal details, names and e-mail addresses of two
referees familiar with your academic performance, CV, your availability and a cover letter (including a
description of your experience as it relates to the job specifications).

Informal inquiries can be made by contacting Dr Graham Ladds (
If you have any questions about the application process please contact Debbie Stanley, pharhr@

Please quote reference PL25258 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections
of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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