skip to primary navigationskip to content
 

Naked mole-rats in the news!

last modified Feb 08, 2018 07:23 PM
Dr Ewan St. John Smith was interviewed on BBC Radio Cambridgeshire to discuss a recent study that was published in Science last week...
Dr Ewan St. John Smith was interviewed on BBC Radio Cambridgeshire (01:53:20) to discuss a recent study that was published in Science last week on which he was an author: Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat. At rest the human brain uses ~25% of the body's energy. Energy production is powered by glucose and oxygen. When someone has a stroke, blood and oxygen stop flowing to part of the brain causing nerve cells to die as they cannot make energy (nerve cell death underlies the disabilities resulting from a stroke). Led by investigators at the Max Delbrück Centre for Molecular Medicine in Berlin and the University of Illinois at Chicago, this recent study found that naked mole-rats can live for up to 18 minutes in the absence of oxygen due to their ability to utilise fructose as an energy source. This work enhances understanding of how nerve cells can function in the absence of oxygen and might lead to work that uncovers novel treatments to prevent brain damage in stroke patients. Dr Smith runs the University of Cambridge Naked Mole-Rat Initiative that brings researchers together understand the highly unusual biology of this rodent: living healthily for 30 years, highly resistant to cancer, insensitive to certain painful stimuli and demonstrating extreme hypoxia resistance.
 
 
« October 2019 »
October
MoTuWeThFrSaSu
123456
78910111213
14151617181920
21222324252627
28293031

RSS Feed Latest news

Pharmacology and Toxicology new link building

Oct 07, 2019

Some of the staff who will occupy the new areas were given a tour by SDC...

Annual David James Lecture

Sep 02, 2019

Title: Human Pain Channelopathies

Pharmacology Lunch-time Run Club

Aug 23, 2019

The Pharmacology Lunch-time Run Club has been going strong since September 2018! We would love to see new faces, so if anyone is interested please join us...

Study led by Gates Cambridge PhD Student Sampurna Chakrabarti

Aug 15, 2019

The group of Dr Ewan St. John Smith have demonstrated that the fluid which lubricates joints plays a key role in osteoarthritic pain...

View all news