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Department of Pharmacology

 
Transformation of naked mole-rat cells

Dr. Walid Khaled & Dr. Ewan Smith had a paper accepted in Nature that has been featured by the University and the Guardian...

Dr. Walid Khaled & Dr. Ewan Smith had a paper accepted in Nature that has been featured by the University and the Guardian.

"Understanding how these remarkable animals are almost completely immune to cancer could improve our understanding of the early stages of the disease in people and lead to new ways to prevent or better treat it.

Until now, it was thought that naked mole-rats almost never got cancer because their healthy cells were resistant to being converted into cancer cells. However, researchers at the University of Cambridge have shown for the first time that genes known to cause cancer in cells of other rodents can also lead naked mole-rat cells to become cancerous."(https://www.cam.ac.uk/research/news/secrets-of-naked-mole-rat-cancer-res...)

Reference: Hadi, F. et al; 'Transformation of naked mole-rat cells,' Nature, July 2020. DOI: 10.1038/s41586-020-2410-x