Abstract:
Amide hydrogen-deuterium exchange is a sensitive probe of the structure, stability and dynamics of proteins. The significant increase in the number of small, model proteins that have been studied has allowed a better understanding of the structural fluctuations that lead to hydrogen exchange. Recent technical advances enable the methodology to be applied to the study of protein-protein interactions in much larger, more complex systems.
Publication ID:
89331
Published date:
February 1998
Publication source:
pubmed
Publication type:
Journal articles
Journal name:
Curr Opin Struct Biol
Publication volume:
8
Publisher:
Parent title:
Edition:
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