You can also access our YouTube playlist here: https://www.youtube.com/playlist?list=PLe8pAmQe8MdGWxOJlmff94P0J0rTn0LEK
Department of Pharmacology Seminar Series Lent 2025
Date |
Speaker |
Topic |
|---|---|---|
| 31 January |
Professor Geoff Woods Principal Investigator, Cambridge Institute for Medical Research |
Human Pain Genetics |
| 3 February |
Professor Pieter Cullis Department of Biochemistry and Molecular Biology, University of British Columbia |
Lipid Nanoparticles that Enable the COVID-19 mRNA vaccines and Gene Therapies |
| 14 February |
Professor David Hughes School of Psychology & Neuroscience, University of Glasgow |
Developing More Effective Pharmacological Treatments for Chronic Pain |
| 21 February |
Dr Alecia-Jane Twigger Cambridge Lactation Lab, University of Cambridge |
Milk it! The Cambridge Lactation Lab Vision |
| 28 February |
Pharmacology Postdoctoral Talks Dr Lay Ping Ong Dr Federico Bosetto |
Cellular therapy for the failing heart - benefits of multicellularity? Aptamers as therapeutic tools against resistant bacteria |
| 5 March |
David James Talk: Dr Feng Zhang Exploration of Biological Diversity |
Exploration of Biological Diversity |
| 7 March |
Dr Florian Merkle Department of Pharmacology, University of Cambridge |
Drug Discovery, Action, and Repurposing in iPSC-derived Neurons |
Department of Pharmacology Seminar Series Lent 2024
Date |
Speaker |
Topic |
|---|---|---|
| 18 October |
Dr Liuhong Chen Vice President of Platform Innovation, Bicycle Therapeutics |
Not too big and not too small – Bicycle peptides for precision targeted therapies |
| 1 November |
Professor Syma Khalid Professor of Computational Microbiology, University of Oxford |
Computational Microbiology of the E. coli cell envelope |
| 8 November |
Dr Ritwick Sawarkar Group Leader, MRC Toxicology, Incoming Pharmacology UTO |
Harnessing the principles of cellular resilience for therapeutics |
| 15 November |
Dr Ivana Bjedov Principal Research Fellow, University College London Cancer Institute |
Delaying and Measuring ageing |
| 22 November |
Prof William McEwan Group Leader, University of Cambridge UK Dementia Research Institute |
Redirecting innate immune mechanisms against aggregated proteins |
| 29 November |
Dr Javier Aguilera Lizarraga Dr Anwit Pandit |
Intestinal nociceptive signalling beyond gut pain and the strength of the ‘naked’ mucosal barrier Determining the principles of target preference and off-target activity of RNAseH recruiting ASOs |
| 6 December |
Dr Thomas Else Research Associate, Sawarkar Group |
Ensuring equity in medical technologies: reducing skin tone bias in photoacoustic imaging |
Department of Pharmacology Seminar Series Lent 2024
Date |
Speaker |
Topic |
|---|---|---|
| 26 January |
Professor Shaun Treweek University of Aberdeen, Health Services Research |
Why it’s important to think about equity, diversity and inclusion when designing, running, analysing and reporting clinical trials |
| 2 February |
Dr Stanislava Panova Astex Pharmaceuticals, Senior Research Associate |
Biophysical methods in small molecule drug discovery |
| 9 February |
Professor Iain Greenwood St George’s University, Department of Life and Environmental Science |
Not just an affair of the heart: A look at ERG channels and Kv7 channels in smooth muscle |
| 16 February |
Dr Alastair Brown Sosei Heptares, Translational Biosciences |
StaRs™ and Structures – a door to the GPCR pharmacological and drug discovery universe |
| 23 February |
Professor Sadaf Farooqi PhD, FRCP, FMedSci, FRS University of Cambridge, Department of Clinical Biochemistry |
David James Seminar: Molecular mechanisms regulating human weight regulation |
| 1 March |
Dr Yu Ye Imperial College London, Department of Brain Science |
A novel type of proteasome condensates that can target toxic protein aggregates |
| 8 March |
Dr Anne Janssen Dr Luke Pattison |
PDRA Talks Nuclear envelope integrity in health and disease A role for the proton-sensing GPCR, GPR65 in inflammatory joint pain |
| 15 March |
Dr Paul Miller University of Cambridge, Department of Pharmacology |
Molecular insights into GABA-A receptor pharmacology |
Department of Pharmacology Seminar Series Michaelmas 2023
Date |
Speaker |
Topic |
Recording |
|---|---|---|---|
| 13th October |
Dr Pietro Sormanni Department of Chemistry, University of Cambridge |
Third-generation approaches of antibody discovery and optimisation |
https://youtu.be/yJfTVV_lhmU |
| 20th October |
Dr Delphine Larrieu Department of Pharmacology, University of Cambridge |
Exploiting nuclear envelope dysfunction in progeria to identify new therapeutic targets for ageing |
https://youtu.be/Tnqjc8G_BPg |
| 3rd November |
Professor Hanns Ulrich Zeilhofer Department of Chemistry and Applied Bioscience |
GABA-A receptor subtypes controlling pain and itch |
https://youtu.be/YB0UxYVGoHk |
| 10th November |
Dr Cintia Roodveldt University of Seville |
Implications and molecular mechanisms of MOK, a new signaling kinase in neurodegenerative neuroinflammation |
Not recorded |
| 17th November |
Dr Stephanie Nestorow (Miller lab) Dr Anthony Keeble (Howarth lab) Department of Pharmacology, University of Cambridge |
A novel mechanism of selective inhibition of Glycine receptors observed by Cryo-EM Controlling and combining signal activation for adhesion and receptor bridging |
Not recorded |
| 24th November |
Professor Henry Colecraft University of Columbia |
Engineering post-translational regulation of ion channels: basic mechanisms to translation |
https://youtu.be/S74s1B5ofY4 |
Department of Pharmacology Seminar Series Lent 2023
Contact Dr Paul Miller for further details.
Date |
Speaker |
Topic |
Recording |
|---|---|---|---|
| 27th January |
Prof Ijeoma Florence Uchegbu University College London
|
Pharmaceutical nanotechnology and the control of in vivo drug transport |
|
| 3rd Febuary |
Dr Cath Lindon Department of Pharmacology, University of Cambridge |
Aurora kinase A: from basic biology to PROTAC-mediated Targeted Protein Degradation |
|
| 10th Febuary |
Dr Kirsty Bannister King’s College London |
The Pharmacology of Pain |
|
| 17th Febuary |
Dr Shafaq Sikander William Harvey Research Institute |
Endogenous and immunological mechanisms of musculoskeletal pain |
|
| 24th Febuary |
Prof Serena Nik-Zainal Academic Dept of Medical Genetics, University of Cambridge |
DNA graffiti: Mutation patterns in human DNA and how to use them in medicine |
|
| 3rd March |
Prof Alessio Ciulli School of Life Sciences, University of Dundee |
How PROTACs work: why the ternary complex matters and how it impacts degrader design |
|
| 10th March |
Dr Paulina Urriola Munoz (Smtih Lab) Dr Maria Zacharopoulou (Itzhaki Lab) Department of Pharmacology, University of Cambridge |
Dysregulation of ADAM10 Shedding activity in naked mole-rat fibroblasts is due to deficient phosphatidylserine externalisation The structural polymorphism of alpha-synuclein in conditions resembling the cellular environment |
|
| 24th March |
Prof Paul Walton Dept of Chemistry, University of York |
Gender equality in academia: why and how |
Department of Pharmacology Tea Club Michaelmas 2022
Contact Dr Paul Miller for further details.
Date |
Speaker |
Topic |
Recording |
|---|---|---|---|
| 14 Ocober at 12:30 |
Prof Mark Howarth Dept of Pharmacology, University of Cambridge
|
Power to the protein: analyse, signal and protect with bacterial superglues |
|
| 21 Ocober at 4pm |
Prof Rick Morimoto Department of Molecular Biophysics, Northwestern University, US |
Translating Proteostasis Mechanisms to Therapeutics of Diseases of Protein Conformation and Aging |
https://zoom.us/rec/share/I8dmKCWqImS_drlWwkr833jn68gPF9tlTcZXc2xxQ7Y1d1... Passcode: &WxHTD2^ |
| 28 October at 12.30 pm |
Dr Shiladitya Sengupta Harvard Medical School, US |
Engineering insights into the strange world of cancer |
|
| 4 November at 12.30 pm |
Dr Sophie Bradley Sosei Heptares, Cambridge |
Targeting M1 muscarinic receptors in neurodegenerative disease |
|
| 11 November at 12.30 pm |
Dr Simon Cook Babraham Institute, University of Cambridge |
TBC |
|
| 18 November at 4:00 pm |
Dr Colleen Noviello Department of Neuroscience, University of Texas Southwestern |
Structural Functions of Cys-loop Receptors in Health and Disease |
|
| 25 November at 12:30 pm |
Dr Dewi Safitri (30 mins) Department of Pharmacology, University of Cambridge Dr Mark Waterhouse (30 mins) Department of Pharmacology, University of Cambridge |
Probing the molecular mechanism of glucose inhibitory polypeptide receptor (GIPR) agonist bias. |
Department of Pharmacology Tea Club Lent 2022
Contact Taufiq Rahman for further details.
Date |
Speaker |
Topic |
|---|---|---|
| 21 January |
Albena Dinkova-Kostova University of Dundee |
Keap1/Nrf2 as a druggable target |
| 28 January |
Kiran Patil MRC-Toxicology Unit, Cambridge |
What drugs do to our bugs |
| 4 February |
Kathryn Lilley Cambridge Centre for Proteomics |
The Dynamic Spatial Organisation Of The Cell |
| 11 february |
Caroline Dart Institute of Systems, Molecular and Integrative Biology, University of Liverpool |
Vascular adenylyl cyclase: New roles for an old enzyme (online) |
| 18 February |
Stefan Marciniak Cambridge Institute of Medical Research, University of Cambridge |
Effects of Z-⍺1-antitrypsin on the endoplasmic reticulum |
| 25 February |
Jenny Gallop Gurdon Institute |
Actin remodelling: from molecular mechanism to disease models |
| 4 March |
Alpha Lee Cavendish Laboratory, University of Cambridge |
The COVID Moonshot: Open Science Discovery of Oral Non-Covalent SARS-CoV-2 Main Protease Inhibitor Therapeutics (In person) |
| 29 April: Annual David James Lecture 2022 |
David Baker Washington University
|
Protein design using deep learning (online).
zoom link https://zoom.us/webinar/register/WN_oWsowrrnQ5- |
Department of Pharmacology Virtual Tea Club Michaelmas Term 2021,
Contact Taufiq Rahman for further details.
Date |
Speaker |
Topic |
|---|---|---|
| 8 October |
Giovanna Zinzalla Karolinska Institute, Sweden, and visiting researcher, Department of Pharmacology, Cambridge, UK |
Transcriptional regulators controlling gene expression programs and cell fate (in person) |
| 15 October |
David Anderson King's College, London, UK |
Antibody mediated pain (online) |
| 22 October |
David Shorthouse MRC Cancer Unit, Cambridge, UK |
Ion channels as novel therapeutic targets in Cancer (in person) |
| 29 October |
Mark Soave University of Nottingham, UK |
Monitoring Allosteric Interactions with CXCR4 using NanoBiT conjugated nanobodies |
| 5 November |
Laura Soucek Vall d'Hebron Institute of Oncology, Spain |
Development of a new generation of anti-Myc mini-proteins for cancer treatment (online) |
| 12 November |
Mohamed Trebak |
The Choreography and native CRAC channels (online) |
| 19 November |
Claire Eyers Institute of Systems, Molecular and Integrative Biology, University of Liverpool, UK |
TBC (online) |
| 26 November |
Nicole Kaneider-Kaser Cambridge Institute of Therapeutic Immunology & Infectious Disease, UK |
The role and function of the GPR35/NaK-ATPase complex (in person) |
Department of Pharmacology Virtual Tea Club Lent Term 2021
Contact Taufiq Rahman for further details.
Date |
Speaker |
Topic |
|---|---|---|
| 22 January |
Ritwick Sawarkar MRC Toxicology Unit, University of Cambridge |
Chromatin response to SARS CoV-2 infection identifies a therapeutic target |
| 29 January |
Maria Marti LMB, Cambridge |
System-specific isoform expression as a physiological driver of GPCR signalling bias |
| 5 February |
Angela Russell Department of Chemistry, University of Oxford |
Discovery of Small Molecules to Manipulate Cell Fate In Vivo: Towards New Therapies for Degenerative Diseases |
| 12 February |
Sarah Ross Babraham Institute |
Oxygen-dependent control of T-cell mediated immunity |
| 19 February |
Jon Gibbins Institute for Cardiovascular and Metabolic Research, University of Reading |
Mind the gap: unexpected ways that blood cells talk to each other |
| 26 February |
Geert Bultynck Laboratory of Molecular and Cellular Signalling, KU Leuven, Belgium |
Anti-apoptotic Bcl-2-family members and Ca2+-signaling control |
| 5 March |
James Thaventhiran MRC Toxicology Unit, University of Cambridge |
TBC |
| 12 March |
Craig M. Crews Yale University |
Annual David James Lecture 2021 PROTAC-mediated Protein Degradation: A New Therapeutic Modality |
| 19 March |
Susan Duty King's College London |
Pre-clinical exploration of neuroprotective strategies for Parkinson’s disease. |
Department of Pharmacology Virtual Tea Club Michaelmas Term 2020
Contact Taufiq Rahman for further details.
Date |
Speaker |
Topic |
|---|---|---|
| 9 October |
Ewan Smith Department of Pharmacology, University of Cambridge |
Driving and Controlling Nociception |
| 16 October |
Roisin Owens Department of Chemical Engineering & Biotechnology, University of Cambridge |
Tissue engineering bioelectronic devices for disease modelling and drug discovery |
| 23 October |
Franziska Denk Wolfson Centre for Age-Related Diseases, King's College London |
Using public RNA sequencing data to benefit your own science – examples from peripheral neuro-immune dysfunction in pain states |
| 30 October |
Will Brackenbury University of York |
Regulation of breast cancer progression by Nav1.5 channels |
| 6 November |
Angeliki Malliri Cancer Research UK Manchester Institute |
Rac GTPase signalling in KRAS mutant non small cell lung cancer |
| 13 November |
Stefan Feske School of Medicine, New York University |
Ion channels in T cell physiology: ORAI, STIM and beyond |
| 20 November |
Beata Wojciak-Stothard National Heart and Lung Institute (NHLI), Imperial College, London |
Kruppel-like factor 2 signalling in pulmonary arterial hypertension/or endothelial dysfunction in PAH |
| 27 November |
Peace Atakpa Department of Pharmacology, University of Cambridge |
An intimate liaison: ER-lysosome Ca2+ cross-talk |