skip to content

Department of Pharmacology

 

Department of Pharmacology Seminar Series Michaelmas 2023

Date

Speaker

Topic

Recording
13th October

Dr Pietro Sormanni

Department of Chemistry, University of Cambridge

Third-generation approaches of antibody discovery and optimisation

https://youtu.be/yJfTVV_lhmU
20th October

Dr Delphine Larrieu

Department of Pharmacology, University of Cambridge

Exploiting nuclear envelope dysfunction in progeria to identify new therapeutic targets for ageing

https://youtu.be/Tnqjc8G_BPg
3rd November

Professor Hanns Ulrich Zeilhofer

Department of Chemistry and Applied Bioscience
ETH Zürich

GABA-A receptor subtypes controlling pain and itch

https://youtu.be/YB0UxYVGoHk
10th November

Dr Cintia Roodveldt

University of Seville

Implications and molecular mechanisms of MOK, a new signaling kinase in neurodegenerative neuroinflammation

Not recorded
17th November

Dr Stephanie Nestorow (Miller lab)

Dr Anthony Keeble (Howarth lab)

Department of Pharmacology, University of Cambridge

A novel mechanism of selective inhibition of Glycine receptors observed by Cryo-EM

Controlling and combining signal activation for adhesion and receptor bridging

Not recorded
24th November

Professor Henry Colecraft

University of Columbia

Engineering post-translational regulation of ion channels: basic mechanisms to translation

https://youtu.be/S74s1B5ofY4

 

Department of Pharmacology Seminar Series Lent 2023

Contact Dr Paul Miller for further details.

Date

Speaker

Topic

Recording
27th January

Prof Ijeoma Florence Uchegbu

University College London

Pharmaceutical nanotechnology and the control of in vivo drug transport

 
3rd Febuary

Dr Cath Lindon

Department of Pharmacology, University of Cambridge

Aurora kinase A: from basic biology to PROTAC-mediated Targeted Protein Degradation

 
10th Febuary

Dr Kirsty Bannister

King’s College London

The Pharmacology of Pain

 
17th Febuary

Dr Shafaq Sikander

William Harvey Research Institute

Endogenous and immunological mechanisms of musculoskeletal pain

 
24th Febuary

Prof Serena Nik-Zainal

Academic Dept of Medical Genetics, University of Cambridge

DNA graffiti: Mutation patterns in human DNA and how to use them in medicine

 
3rd March

Prof Alessio Ciulli

School of Life Sciences, University of Dundee

How PROTACs work: why the ternary complex matters and how it impacts degrader design

 
10th March

Dr Paulina Urriola Munoz (Smtih Lab)

Dr Maria Zacharopoulou (Itzhaki Lab)

Department of Pharmacology, University of Cambridge

Dysregulation of ADAM10 Shedding activity in naked mole-rat fibroblasts is due to deficient phosphatidylserine externalisation

The structural polymorphism of alpha-synuclein in conditions resembling the cellular environment

 
24th March

Prof Paul Walton

Dept of Chemistry, University of York

Gender equality in academia: why and how

 

 

Department of Pharmacology Tea Club Michaelmas 2022

Contact Dr Paul Miller for further details.

Date

Speaker

Topic

Recording
14 Ocober at 12:30

Prof Mark Howarth

Dept of Pharmacology, University of Cambridge

 

Power to the protein: analyse, signal and protect with bacterial superglues

 
21 Ocober at 4pm

Prof Rick Morimoto

Department of Molecular Biophysics, Northwestern University, US

Translating Proteostasis Mechanisms to Therapeutics of Diseases of Protein Conformation and Aging

https://zoom.us/rec/share/I8dmKCWqImS_drlWwkr833jn68gPF9tlTcZXc2xxQ7Y1d1...
Passcode: &WxHTD2^
28 October at 12.30 pm

Dr Shiladitya Sengupta

Harvard Medical School, US

Engineering insights into the strange world of cancer

 
4 November at 12.30 pm

Dr Sophie Bradley

Sosei Heptares, Cambridge

Targeting M1 muscarinic receptors in neurodegenerative disease

 
11 November at 12.30 pm

Dr Simon Cook

Babraham Institute, University of Cambridge

TBC

 
18 November at 4:00 pm

Dr Colleen Noviello

Department of Neuroscience, University of Texas Southwestern

Structural Functions of Cys-loop Receptors in Health and Disease

 
25 November at 12:30 pm

Dr Dewi Safitri (30 mins)

Department of Pharmacology, University of Cambridge

Dr Mark Waterhouse (30 mins)

Department of Pharmacology, University of Cambridge

Probing the molecular mechanism of glucose inhibitory polypeptide receptor (GIPR) agonist bias.

 

 

Department of Pharmacology Tea Club Lent 2022

Contact Taufiq Rahman for further details.

Date

Speaker

Topic

21 January

Albena Dinkova-Kostova

University of Dundee

Keap1/Nrf2 as a druggable target
28 January

Kiran Patil

MRC-Toxicology Unit, Cambridge

What drugs do to our bugs
4 February

Kathryn Lilley

Cambridge Centre for Proteomics

The Dynamic Spatial Organisation Of The Cell
11 february

Caroline Dart

Institute of Systems, Molecular and Integrative Biology, University of Liverpool

Vascular adenylyl cyclase: New roles for an old enzyme (online)
18 February

Stefan Marciniak

Cambridge Institute of Medical Research, University of Cambridge

Effects of Z-⍺1-antitrypsin on the endoplasmic reticulum
25 February

Jenny Gallop

Gurdon Institute

Actin remodelling: from molecular mechanism to disease models
4 March

Alpha Lee

Cavendish Laboratory, University of Cambridge

The COVID Moonshot: Open Science Discovery of Oral Non-Covalent SARS-CoV-2 Main Protease Inhibitor Therapeutics (In person)
29 April: Annual David James Lecture 2022

David Baker

Washington University

 

Protein design using deep learning (online).

 zoom link https://zoom.us/webinar/register/WN_oWsowrrnQ5-
LiMi6OtktrQ

 

 

Department of Pharmacology Virtual Tea Club  Michaelmas Term 2021,

Contact Taufiq Rahman for further details.

 

Date

Speaker

Topic

8 October

Giovanna Zinzalla

Karolinska Institute, Sweden, and visiting researcher, Department of Pharmacology, Cambridge, UK

Transcriptional regulators controlling gene expression programs and cell fate (in person)
15 October

David Anderson

King's College, London, UK

Antibody mediated pain (online)
22 October

David Shorthouse

MRC Cancer Unit, Cambridge, UK

Ion channels as novel therapeutic targets in Cancer (in person)
29 October

Mark Soave

University of Nottingham, UK

Monitoring Allosteric Interactions with CXCR4 using NanoBiT conjugated nanobodies
5 November

Laura Soucek

Vall d'Hebron Institute of Oncology, Spain

Development of a new generation of anti-Myc mini-proteins for cancer treatment (online)
12 November

Mohamed Trebak

The Choreography and native CRAC channels (online)
19 November

Claire Eyers

Institute of Systems, Molecular and Integrative Biology, University of Liverpool, UK

TBC (online)
26 November

Nicole Kaneider-Kaser

Cambridge Institute of Therapeutic Immunology & Infectious Disease, UK

The role and function of the GPR35/NaK-ATPase complex (in person)

Department of Pharmacology Virtual Tea Club Lent Term 2021

 

Contact Taufiq Rahman for further details.

 

Date

Speaker

Topic

22 January

Ritwick Sawarkar

MRC Toxicology Unit, University of Cambridge

Chromatin response to SARS CoV-2 infection identifies a therapeutic target
29 January

Maria Marti

LMB, Cambridge

System-specific isoform expression as a physiological driver of GPCR signalling bias
5 February

Angela Russell

Department of Chemistry, University of Oxford

Discovery of Small Molecules to Manipulate Cell Fate In Vivo: Towards New Therapies for Degenerative Diseases
12 February

Sarah Ross

Babraham Institute

Oxygen-dependent control of T-cell mediated immunity
19 February

Jon Gibbins

Institute for Cardiovascular and Metabolic Research, University of Reading

Mind the gap: unexpected ways that blood cells talk to each other
26 February

Geert Bultynck

Laboratory of Molecular and Cellular Signalling, KU Leuven, Belgium

Anti-apoptotic Bcl-2-family members and Ca2+-signaling control
5 March

James Thaventhiran

MRC Toxicology Unit, University of Cambridge

TBC
12 March

Craig M. Crews

Yale University

Annual David James Lecture 2021
PROTAC-mediated Protein Degradation: A New Therapeutic Modality
19 March

Susan Duty

King's College London

Pre-clinical exploration of neuroprotective strategies for Parkinson’s disease.

 

 

Department of Pharmacology Virtual Tea Club Michaelmas Term 2020

 

Contact Taufiq Rahman for further details.

 

Date

Speaker

Topic

9 October

Ewan Smith

Department of Pharmacology, University of Cambridge

Driving and Controlling Nociception
16 October

Roisin Owens

Department of Chemical Engineering & Biotechnology, University of Cambridge

Tissue engineering bioelectronic devices for disease modelling and drug discovery
23 October

Franziska Denk

Wolfson Centre for Age-Related Diseases, King's College London

Using public RNA sequencing data to benefit your own science – examples from peripheral neuro-immune dysfunction in pain states
30 October

Will Brackenbury

University of York

Regulation of breast cancer progression by Nav1.5 channels
6 November

Angeliki Malliri

Cancer Research UK Manchester Institute

Rac GTPase signalling in KRAS mutant non small cell lung cancer
13 November

Stefan Feske

School of Medicine, New York University

Ion channels in T cell physiology: ORAI, STIM and beyond
20 November

Beata Wojciak-Stothard

National Heart and Lung Institute (NHLI), Imperial College, London

Kruppel-like factor 2 signalling in pulmonary arterial hypertension/or endothelial dysfunction in PAH
27 November

Peace Atakpa

Department of Pharmacology, University of Cambridge

An intimate liaison: ER-lysosome Ca2+ cross-talk