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Department of Pharmacology

 
Author(s): 
Watson, LD, Maynard, P, Cullen, DC, Sethi, RS, Brettle, J, Lowe, CR
Abstract: 

The fabrication and operation of a microelectronic conductimetric biosensor is described. The device monitors the change in solution conductance occasioned by the catalytic action of enzymes immobilised over a planar conductance cell comprising serpentined and interdigitated metal conductor tracks. The output of the instrument was linear over a 3 min period on addition of urea to a sample cell overlaid with immobilised urease. The responses to any given urea concentration were reproducible to within approximately ±1%. The device responds to urea present in serum samples. © 1987, Elsevier Applied Science Publishers Ltd. All rights reserved.

Publication ID: 
218393
Published date: 
1 January 1987
Publication source: 
scopus
Publication type: 
Journal articles
Journal name: 
Topics in Catalysis
Publication volume: 
3
Publisher: 
Parent title: 
Edition: 
Publication number: