Red-light modulated ortho-chloro azobenzene photoswitch for peptide stapling via aromatic substitution

Author(s):

Kapun, M, Pérez-Areales, FJ, Ashman, N, Rowling, PJE, Schober, T, Fowler, E, Itzhaki, LS, Spring, DR

Abstract:

<jats:p>Development and proof-of-concept for a photoswitchable peptide staple with the ability to trigger a major change in binding affinity upon visible light irradiation.</jats:p>

Publication ID:

1551149

DOI link:

10.1039/d3cb00176h

Published date:

December 2024 (Published online)

Publication source:

crossref

Publication type:

Journal articles

Journal name:

RSC Chemical Biology

Publication volume:

Publisher:

Royal Society of Chemistry (RSC)

Parent title:

Edition:

Publication number:

Red-light modulated <i>ortho</i>-chloro azobenzene photoswitch for peptide stapling <i>via</i> aromatic substitution

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