Our research focuses on the use of DNA as a building material, specifically one that can be used to create antimicrobial drug delivery vehicles. The two main lines of our research focus on DNA nanostructure development, for optimal interaction with their bacterial targets and on aptamer selection for bacterial outer membrane proteins.
To achieve these goals we use a range of state-of-the-art approaches. We use high-speed atomic force microscopy in combination with superresolution microscopy, to assess the successful synthesis of DNA nanostructures and their interaction with their bacterial targets. For aptamer selection, we use SELEX and combine the technique with microfluidic devices, to achieve rapid, accurate and reproducible results. Through a wide network of collaborations, both in the UN and internationally, we explore different approaches that can enrich and expand the scope of our research.
Find out more about our research here:
New Scientist:https://www.newscientist.com/article/2227371-tiny-machines-made-of-dna-o...
CGTN Razor: https://www.youtube.com/watch?v=ndrUFSCDyDw