Structure, function and chemico-biological regulation of ion channels

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Dr Taufiq Rahman-  Group Leader                                                             

University Associate Professor

Fellow at Murray Edwards College.

e-mail: mtur2@cam.ac.uk

Tel:+44-01223 334068/334061

Fax: +44 1223 334100; Twitter: @RahmanLab

Available for Consultancy

Keywords

Calcium signalling, single channel recordings, structural bioinformatics, rational drug design, molecular modelling, electrophysiology, drug repositioning, ion channels

Investigator Biography

Taufiq's early academic training was in pharmaceutical sciences with a Bachelor and a Master of Pharmacy (B.Pharm and M.Pharm) degrees from University of Dhaka, Bangladesh. His earlier research interest included ethnopharmacology and chemistry of bioactive natural products. After spending a year in Dhaka as a lecturer of pharmacy, he pursued an MSc in Molecular Pharmacology in the University of Manchester under the Commonwealth Scholarship and Fellowship program in 2003. During the MSc, he worked in the Smooth Muscle Research Group and developed interest in ion channels and associated signalling pathways.  In 2005, he started a PhD under the supervision of Professor Colin Taylor in this Department. During this time,  he studied some fundamental biophysical properties and regulatory aspects of inositol-1,4,5 trisphosphate receptors (IP₃Rs) at the single channel level. After the completion of his PhD in 2008, he continued research in the same lab initially as a post doc and then from October 2009, he started his first independent position as a Drapers’ Research Fellow at Pembroke College. In the last five years, he has continued research in calcium signalling and developed a strong parallel interest in rational designing and development of chemical probes and modulators of ion channels and other signalling proteins. In 2011, he received the Early Career Research Award in Signal Transduction from the Biochemical Society. From  October 2012 till September 2017, he worked as a Royal Society University Research Fellow in the Department. Alongside this, he started his position as a University Lecturer in 2016. In 2022, he became University Associate Professor.