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Research Interest

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As a research lab, we are essentially 'small molecule-centric'. We employ state-of-the art in silico approaches coupled with prospective, complementary wet experiments (calcium imaging, electrophysiology, biochemical and biophysical assays) to know the molecular mechanisms underlying the ligand recognition, ligand modulation, structural variation and evolution of some calcium-permeable ion channels.

We are pursuing rational development of novel chemical probes/modulators of these ion channels. Additionally, we are actively engaged in collaborative research for rational development of novel chemical scaffolds/leads against some protein targets implicated in microbial infections, cancer, pain and diabetes.


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