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Department of Pharmacology

 

 

Group Leader

Graham Ladds PhD FBPhS

Professor in Receptor Pharmacology and fellow of St John’s college. Fellow of the British Pharmacological society

Email: grl30@cam.ac.uk

Twitter: @GpcrL

 

 

 

 

 

 

 

Postdoctoral Research Fellows

Dr Matthew Harris

Matt completed his BBSRC funded PhD in 2019. His work focused on investigating the role that receptor activity modifying proteins (RAMPs) and small molecules play in modulating gastric inhibitory polypeptide receptor (GIPR) signalling. Matt is now a junior research fellow of St Edmund’s College, and his post-doctoral research continues to explore the effects of RAMPs on GPCR function.

Email: mh702@cam.ac.uk

 

 

 

 

 

 

Dr Dewi Safitri

For her PhD she worked on modulation of cAMP through PDE inhibition and its therapeutic potential. Her current post-doctoral project is investigating glucose-dependent insulinotropic polypeptide receptor (GIPR) pharmacology and how it is influenced by RAMP association. The project is conducted with Takeda Pharmaceutical as the industrial partner.

Email: ds791@cam.ac.uk

Twitter: @dewi_safitri_88

 

 

 

 

 

 

Graduate students

Ms Abigail Pearce

Abi is a BBSRC iCASE student at King’s College, in partnership with AstraZeneca. She completed her undergraduate degree at the University of Cambridge, before beginning her PhD in 2018. She looks at the signalling at the Glucagon subfamily of GPCRs, focusing on the Glucagon-like peptide-1 receptor (GLP1R) and how its interactions with other proteins regulate insulin secretion.

Email: ap847@cam.ac.uk

Twitter: @abi_pearce96

 

 

 

 

 

Ms Anna Suchankova

Anna is a PhD student funded by the Cambridge Trust. She completed her undergraduate degree in Natural Sciences at the University of Cambridge, starting her PhD in 2019. She looks at allosteric modulators of GPCR signalling, focusing on the gastric inhibitory polypeptide receptor (GIPR), as well as the adenosine family of receptors.

Email: as2268@cam.ac.uk

 

 

 

 

 

 

 

Mr Matthew Rosa

Matt is a PhD student funded by AstraZeneca. He completed his Undergraduate and Masters degrees at the University of Aberdeen, before starting his PhD in 2020. He looks at the family 1 taste receptors, specifically those contributing to ‘sweet’ chemosensing, and how these can be tuned in order to develop a glucose biosensor.

Email: mr857@cam.ac.uk

 

 

 

 

 

 

 

Mr Theo Redfern-Nichols

Theo is a BBSRC iCASE PhD student at Wolfson College, in partnership with AstraZeneca. He completed his undergraduate degree in Natural Sciences at the University of Cambridge before beginning his PhD in 2020. He is interested in GPCR bias signalling. Specifically, Theo is investigating the Calcitonin Receptor-like Receptor (CLR) and its interactions with receptor activity modifying proteins (RAMPs).

Email: tr428@cam.ac.uk

 

 

 

 

 

 

Mr Edward Wills

Ned is a PhD student funded through the EPSRC Sensor CDT by AstraZeneca. After completing his MSci in Neuroscience at University College London, he studied an MRes in Sensor Technologies here at Cambridge before beginning his PhD in 2021. Ned aims to develop novel molecular biosensors for intracellular GPCR signalling pathways, with a focus on high throughput drug screening.

Email: ehw34@cam.ac.uk

 

 

 

 

 

 

Ms Xianglin (Rosalind) Huang

Rosalind developed great interest in receptor pharmacology during her undergraduate in Pharmacology and Systems Biology in Natural sciences at University of Cambridge. She is funded by CSC Cambridge International Scholarship and starts her PhD in 2021. Her project is to understand the interactions and mechanisms of regulation between GPCRs, ligands and G proteins/β-arrestin/RAMPs by employing both computational and pharmacological approaches.

Email: xh290@cam.ac.uk

 

 

 

 

 

 

 

Lab alumni

Post-2010

Dr Liliya Kopanitsa, former post-doctoral visitor

Mr Tim Noel, former MPhil student, applying for PhD places

Ms Sabrina Carvalho, former PhD student, currently a Research Scientist at AstraZeneca

Dr Kerry Barkan, former post-doc and PhD student, currently a Research Scientist at Sosei Heptares

Dr Ashley Clark, former PhD student

Dr Ho Yan Yeung, former PhD student, currently a post-doc at Copenhagen University

Mr Hitoshi Yamauchi, former MPhil student

Dr Ian Winfield, former post-doc and PhD student, currently Team Leader at Domainex

Dr Alex Esparza-Franco, former PhD student, currently Scientific Officer at Micropathology Ltd

Dr Cathryn Weston, post-doc and PhD student, currently Career Development Fellow for Asthma UK, University of Leicester

Dr Catherine Richardson, former PhD student, currently Associate Consultant, Healthcare

Dr Anthony Knight, former PhD student, left Science to become an accountant

 

Pre-2010

Ms Jannette Bennett

Dr Wayne Croft

Dr Antonio Lock

Dr Louise Godfrey

Dr Benjamin Smith

Dr Claire Hill

Dr Rachel Forfar