skip to primary navigationskip to content
 

Dr Catherine Lindon

Dr Catherine Lindon

University Lecturer


Office Phone: +44 (0) 1223 3 33964 / Lab: 7 65927

Keywords

  • Ubiquitin, APC/C, proteolysis, Aurora kinase, mitotic exit, cell fate, cancer

Topics

  • Cancer and Infectious Diseases

Key Publications

  • Min M, Mayor U, Dittmar G, Lindon C (2014). Using in vivo-biotinylated ubiquitin to describe a mitotic exit ubiquitome from human cells. Molecular & Cellular Proteomics 13 2411-2425
  • Floyd S, Whiffin N, Gavilan MP, Kutscheidt S, De Luca M, Marcozzi C, Watkins J, Chung K, Fackler O, Lindon C (2013). Spatiotemporal organization of Aurora B activity by APC/C-Cdh1 after mitosis coordinates cell spreading via FHOD1. J. Cell Sci., 126 2845-2856
  • Connell J, Lindon C, Luzio J, Reid E (2009). Spastin couples microtubule severing to membrane traffic in completion of cytokinesis and secretion. Traffic 10 42-56
  • Floyd S, Pines J, Lindon C (2008). APC/C-Cdh1 targets Aurora Kinases to control mitotic spindle reorganization at anaphase.  Current Biology 18 1649-1658
  • Lindon C, Pines J (2004). Ordered proteolysis in anaphase inactivates Plk1 to contribute to proper mitotic exit in human cells. J. Cell Biol. 164 233-241


Investigator biography

Cath discovered her interest in cell biology at the Institut Pasteur in Paris, during postdoctoral studies of myogenic cell fate control. She returned to the UK with a Wellcome Trust Advanced Training Fellowship, to acquire expertise in live cell imaging of human cells with the Pines group at the Gurdon Institute in Cambridge. She subsequently set up her own research programme to study ubiquitin-mediated events in mitotic exit, with the support of a Career Development Award from the MRC. In 2008 she became a research group leader in the Department of Genetics and in 2015 has taken up a lectureship in the Department of Pharmacology.