Lindon Lab, October 2018
Cath - Anja - Cynthia - Richard
Begum - Thomas -Ahmed - Siân - Cami
Current members:
Dr Begum Akman
Ahmed Abdelbaki
Richard Wang
Richard completed his undergraduate studies at the University of Cambridge where he specialised in Pharmacology for his Bachelor of Arts and Systems Biology for his Master in Science. His BA project with Dr Tai-Ping Fan at the Pharmacology department involved characterising and identifying the targets of a new molecular entity derived from Chinese Traditional Medicine. His MSci project was in the Ralser lab at the Biochemistry department, where he explored a metabalomics approach in charactering gene functions by utilising amino acid signatures. He joined the Lindon lab in 2017 for his PhD on the BBSRC DTP after doing a rotation project in the Segal Lab at Genetics looking at asymmetry breaking during cell division in S. Cerevisiae. In the Lindon lab, Richard is investigating the use of Tandem fluorescent timer tags in measuring AURKA stability and the novel class of PROTAC drugs in targeting AURKA for degradation. Outside the lab, Richard enjoys playing hockey, collecting coins, and engaging in College activities.
Camilla Ascanelli
Camilla, originally from Italy, moved to the UK to undertake a Bachelor degree in Pharmacology at Newcastle University. Here, she characterised the effect of an inhibitor of Haspin on Histone H3 phosphorylation and chromosomal segregation.
After graduating, Camilla went on to work for a year at the Mario Negri Institute for Pharmacological Research, Italy, where she focussed on CRISPR-Cas9-Mediated Correction of the G189R-PAX2 Mutation in Induced Pluripotent Stem Cells from a Patient with Focal Segmental Glomerulosclerosis.
In 2017 she joined the Lindon Lab for a PhD under the Astra-Zeneca Ph.D. studentship. Her project concerns developing and characterising a novel live-cell imaging assay to measure Myc oncoprotein's stability.
Some of her hobbies and interests include traveling, art and music.
Siân Stockton
Siân studied at Imperial College London before coming to Cambridge, where she took up rowing at Darwin. Her BBSRC-DTP funded PhD project Construction and biological characterisation of a custom engineered protein degradation tool is a collaboration between the Lindon and Itzhaki labs.
Cynthia Okoye
Cynthia completed her BA Hons in Chemistry (with a concentration in Biochemistry and Molecular Biology) at Williams College, Massachusetts in 2018 and joined the Lindon and Itzhaki labs for a PhD under the Gates Cambridge scholarship. Her project aims to discover peptide binders of the APC/C in order to harness the E3 ligase for PROTAC therapeutics. Some of her hobbies and interests include Zumba and African dance, Korean drama, Gospel music, and traveling.
Roberta Cacioppo
Roberta obtained a Bachelor’s degree in Biotechnologies from the University of Palermo in Italy, where she investigated the role of the long non-coding RNA hsrω in TDP-43 protein homeostasis. During her Master’s degree she undertook a research project at the MRC Protein Phosphorylation and Ubiquitylation Unit in Dundee UK, exploring the translation of proteasome assembly chaperones during cellular stress. She joined the Lindon Lab in 2019 as a David James PhD Student and will be studying the post-transcriptional regulation of Aurora kinase A expression.Outside the lab she enjoys cooking, volunteering and travelling.
Former members:
Arianna Rossi
Anja Hagting
Thomas Brand
Matteo Conversano
Rhys Grant
Mingwei Min
Alessia Bertholdi
Chiara Marcozzi
Maria P. Gavilan
Shan Qiao
Maria De Luca
Suzanne Floyd